1-(2-carboethoxyethyl)-5-oxoproline ethyl ester

Base Information

• Chemical Name: 1-(2-carboethoxyethyl)-5-oxoproline ethyl ester
• CAS No.: 41563-76-2
• Molecular Formula: C₁₂H₁₉NO₅
• Molecular Weight: 257.287
• Mol file: 41563-76-2.mol

Synonyms:

Chemical Property of 1-(2-carboethoxyethyl)-5-oxoproline ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 1-(2-carboethoxyethyl)-5-oxoproline ethyl ester

There total 2 articles about 1-(2-carboethoxyethyl)-5-oxoproline ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

Ethyl 3-bromopropionate (539-74-2) + ethyl (S)-pyroglutamate (7149-65-7) → 1-(2-carboethoxyethyl)-5-oxoproline ethyl ester (41563-76-2,5447-61-0)

Guidance literature:

With sodium hydride; In tetrahydrofuran; paraffin; at 0 ℃; 20-30 min;

DOI:10.1080/00397919608002625

Reference yield:

N-(2-cyano-ethyl)-L-glutamic acid (90243-80-4) → 1-(2-carboethoxyethyl)-5-oxoproline ethyl ester (41563-76-2,5447-61-0)

Guidance literature:

With hydrogenchloride; ethanol; Erwaermen des Reaktionsgemisches;

DOI:10.1021/ja01140a059

upstream raw materials:

N-(2-cyano-ethyl)-L-glutamic acid

Ethyl 3-bromopropionate

ethyl (S)-pyroglutamate