Benzeneacetaldehyde, a-thioxo-, dimethylhydrazone

Base Information

• Chemical Name: Benzeneacetaldehyde, a-thioxo-, dimethylhydrazone
• CAS No.: 136209-69-3
• Molecular Formula: C₁₀H₁₂N₂S
• Molecular Weight: 192.285
• Mol file: 136209-69-3.mol

Synonyms:

Chemical Property of Benzeneacetaldehyde, a-thioxo-, dimethylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzeneacetaldehyde, a-thioxo-, dimethylhydrazone

There total 2 articles about Benzeneacetaldehyde, a-thioxo-, dimethylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

2-oxo-2-phenylacetaldehyde dimethylhydrazone (65296-01-7) → 2-(Dimethyl-hydrazono)-1-phenyl-ethanethione (136209-69-3)

Guidance literature:

With Lawessons reagent; In benzene; a.) 10 deg C, 5 min, b.) up to room temp., 10 min;

DOI:10.1055/s-1991-26513

Reference yield:

2,2-dihydroxy-1-phenyl-ethanone (1075-06-5) → 2-(Dimethyl-hydrazono)-1-phenyl-ethanethione (136209-69-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / ethanol / 24 h / Ambient temperature

2: 50 percent / Lawesson's reagent / benzene / a.) 10 deg C, 5 min, b.) up to room temp., 10 min

With Lawessons reagent; In ethanol; benzene;

DOI:10.1055/s-1991-26513

Reference yield: 53.0%

N-phenyl-maleimide (941-69-5) + 2-(Dimethyl-hydrazono)-1-phenyl-ethanethione (136209-69-3) → 4-Dimethylamino-2,6-diphenyl-4a,7a-dihydro-4H-pyrrolo[3,4-b][1,4]thiazine-5,7-dione (145223-87-6)

Guidance literature:

In benzene; for 3h; Ambient temperature;

upstream raw materials:

2-oxo-2-phenylacetaldehyde dimethylhydrazone

2,2-dihydroxy-1-phenyl-ethanone

Downstream raw materials:

4-Dimethylamino-2,6-diphenyl-4a,7a-dihydro-4H-pyrrolo[3,4-b][1,4]thiazine-5,7-dione

1-(4-Dimethylamino-6-phenyl-3,4-dihydro-2H-[1,4]thiazin-3-yl)-ethanone

4-Dimethylamino-6-phenyl-3,4-dihydro-2H-[1,4]thiazine-3-carbonitrile

4-Dimethylamino-6-phenyl-3,4-dihydro-2H-[1,4]thiazine-3-carboxylic acid methyl ester