methyl 1-(4-nitrophenyl)-2-phenylcyclopropanecarboxylate

Base Information

• Chemical Name: methyl 1-(4-nitrophenyl)-2-phenylcyclopropanecarboxylate
• CAS No.: 129919-24-0
• Molecular Formula: C₁₇H₁₅NO₄
• Molecular Weight: 297.31
• Mol file: 129919-24-0.mol

Synonyms:

Chemical Property of methyl 1-(4-nitrophenyl)-2-phenylcyclopropanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 1-(4-nitrophenyl)-2-phenylcyclopropanecarboxylate

There total 6 articles about methyl 1-(4-nitrophenyl)-2-phenylcyclopropanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + methyl 2-diazo-2-(4-nitrophenyl)acetate (22812-58-4) → C18H14N2O8 + methyl 1-(4-nitrophenyl)-2-phenylcyclopropanecarboxylate (129919-24-0,129919-25-1)

Guidance literature:

With C₄₀H₄₂N₂O₁₀Rh₂S₂; In 1,2-dichloro-ethane; at 80 ℃; Reagent/catalyst; Solvent; Temperature; Overall yield = 59 %Spectr.; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.inorgchem.8b02627

Reference yield:

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + methyl (4-nitrophenyl)acetate (2945-08-6) → methyl 1-(4-nitrophenyl)-2-phenylcyclopropanecarboxylate (129919-24-0,129919-25-1) + methyl 1-(4-nitrophenyl)-2-phenylcyclopropanecarboxylate (129919-24-0,129919-25-1)

Guidance literature:

methyl (4-nitrophenyl)acetate; With sodium hydride; In acetonitrile; at 0 - 20 ℃; for 0.333333h; Inert atmosphere;

With [bis(acetoxy)iodo]benzene; In acetonitrile; at -10 - 10 ℃; for 0.333333h; Inert atmosphere;

styrene; In acetonitrile; at 10 ℃; for 3h; Overall yield = 42percent; Overall yield = 0.012 g; chemoselective reaction; Inert atmosphere; Irradiation;

DOI:10.1002/anie.201908994

Reference yield:

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + methyl (4-nitrophenyl)acetate (2945-08-6) → methyl 1-(4-nitrophenyl)-2-phenylcyclopropanecarboxylate (129919-24-0,129919-25-1) + methyl 1-(4-nitrophenyl)-2-phenylcyclopropanecarboxylate (129919-24-0,129919-25-1)

Guidance literature:

methyl (4-nitrophenyl)acetate; With sodium hydride; In acetonitrile; at 0 - 20 ℃; for 0.333333h; Inert atmosphere;

With [bis(acetoxy)iodo]benzene; In acetonitrile; at -10 - 10 ℃; for 0.333333h; Inert atmosphere;

styrene; In acetonitrile; at 10 ℃; for 3h; Overall yield = 42percent; Overall yield = 0.012 g; chemoselective reaction; Inert atmosphere; Irradiation;

DOI:10.1002/anie.201908994

upstream raw materials:

styrene

methyl 2-diazo-2-(4-nitrophenyl)acetate

methyl (4-nitrophenyl)acetate