diethyl (3,4-dihydroquinolin-1(2H)-ylmethylidene)propanedioate

Base Information

Chemical Name:diethyl (3,4-dihydroquinolin-1(2H)-ylmethylidene)propanedioate
CAS No.:6687-87-2
Molecular Formula:C₁₇H₂₁NO₄
Molecular Weight:303.358
Hs Code.:
NSC Number:87839
DSSTox Substance ID:DTXSID50293208

Synonyms:6687-87-2;NSC87839;ST50846277;SCHEMBL3980445;DTXSID50293208;FRULCXSCLFPAIU-UHFFFAOYSA-N;diethyl (3,4-dihydroquinolin-1(2H)-ylmethylidene)propanedioate;NSC-87839;STK443034;AKOS003330966;Diethyl 2-((3,4-dihydro-2H-quinolin-1-yl)methylene)malonate

Suppliers and Price of diethyl (3,4-dihydroquinolin-1(2H)-ylmethylidene)propanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of diethyl (3,4-dihydroquinolin-1(2H)-ylmethylidene)propanedioate

Chemical Property:

Vapor Pressure:5.31E-06mmHg at 25°C
Boiling Point:380.8°C at 760 mmHg
Flash Point:184.1°C
Density:1.201g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:303.14705815
Heavy Atom Count:22
Complexity:412

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(=CN1CCCC2=CC=CC=C21)C(=O)OCC

Technology Process of diethyl (3,4-dihydroquinolin-1(2H)-ylmethylidene)propanedioate

There total 2 articles about diethyl (3,4-dihydroquinolin-1(2H)-ylmethylidene)propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 635-46-1
1,2,3,4-tetrahydroisoquinoline

: 87-13-8
diethyl 2-ethoxymethylenemalonate

: 6687-87-2
(3,4-dihydro-2H-quinolin-1-ylmethylene)-malonic acid diethyl ester

Guidance literature:: at 130 ℃; for 1h;

Reference yield:

: 6687-87-2
(3,4-dihydro-2H-quinolin-1-ylmethylene)-malonic acid diethyl ester

Guidance literature:: entspr. Amin, Ethoxymethylenmalonsaeurediethylester;
DOI:10.1021/jm00282a001

Reference yield:

: 6687-87-2
(3,4-dihydro-2H-quinolin-1-ylmethylene)-malonic acid diethyl ester

: 797785-46-7
10-(2-benzyloxy-ethylamino)-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: PPA / 4 h / 110 °C

2: sulfuric acid; nitric acid / 3 h / 0 °C

3: hydrogenchloride / iron / water / 15 h / 20 °C

4: sodium cyanoborohydride; acetic acid / methanol / 3 h / 20 °C

With hydrogenchloride; PPA; sulfuric acid; nitric acid; sodium cyanoborohydride; acetic acid; iron; In methanol; water;