3-hexylserine

Base Information

• Chemical Name: 3-hexylserine
• CAS No.: 50730-85-3
• Molecular Formula: C₉H₁₉NO₃
• Molecular Weight: 189.255
• Mol file: 50730-85-3.mol

Synonyms:

Chemical Property of 3-hexylserine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

3-hexylserine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-hexylserine

There total 11 articles about 3-hexylserine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Dibenzylamino-3-hydroxy-nonanoic acid (118965-99-4,118966-03-3) → 2-Amino-3-hydroxy-pelargonsaeure (50730-85-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 70 ℃; Yield given;

DOI:10.1016/S0040-4039(01)91236-5

Reference yield:

heptanal (111-71-7) → 2-Amino-3-hydroxy-pelargonsaeure (50730-85-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) LDA / 1.) THF, -60 deg C, 2.) -60 deg C

2: 0.5 N KOH / methanol; H₂O

3: H₂ / Pd/C / aq. ethanol / 70 °C

With potassium hydroxide; hydrogen; lithium diisopropyl amide; palladium on activated charcoal; In methanol; ethanol; water;

DOI:10.1016/S0040-4039(01)91236-5

Reference yield:

Heptanoic acid chloride (2528-61-2) → 2-Amino-3-hydroxy-pelargonsaeure (50730-85-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) LDA / 1.) THF, -60 deg C, 2.) -60 deg C

2: NaBH₄, NH₄Cl buffer / aq. ethanol

3: 0.5 N KOH / methanol; H₂O

4: H₂ / Pd/C / aq. ethanol / 70 °C

With potassium hydroxide; sodium tetrahydroborate; NH₄Cl buffer; hydrogen; lithium diisopropyl amide; palladium on activated charcoal; In methanol; ethanol; water;

DOI:10.1016/S0040-4039(01)91236-5

upstream raw materials:

heptanal

acetylamino-malonic acid monomethyl ester

copper(II) glycinate

Ethyl-(1,2-diacetoxy-octyl)-ether