3-(1,3-dioxolan-2-yl)-2-<3-p-tolyl-5-(4-hydroxy-3-methoxybenzylidene)-4-thiazolidinon-2-ylidene>hydrazinoquinoline

Base Information

• Chemical Name: 3-(1,3-dioxolan-2-yl)-2-<3-p-tolyl-5-(4-hydroxy-3-methoxybenzylidene)-4-thiazolidinon-2-ylidene>hydrazinoquinoline
• CAS No.: 128348-93-6
• Molecular Formula: C₃₀H₂₆N₄O₅S
• Molecular Weight: 554.626
• Mol file: 128348-93-6.mol

Synonyms:

Chemical Property of 3-(1,3-dioxolan-2-yl)-2-<3-p-tolyl-5-(4-hydroxy-3-methoxybenzylidene)-4-thiazolidinon-2-ylidene>hydrazinoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(1,3-dioxolan-2-yl)-2-<3-p-tolyl-5-(4-hydroxy-3-methoxybenzylidene)-4-thiazolidinon-2-ylidene>hydrazinoquinoline

There total 4 articles about 3-(1,3-dioxolan-2-yl)-2-<3-p-tolyl-5-(4-hydroxy-3-methoxybenzylidene)-4-thiazolidinon-2-ylidene>hydrazinoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-3-quinoline carboxaldehyde (73568-25-9) → 3-(1,3-dioxolan-2-yl)-2-<3-p-tolyl-5-(4-hydroxy-3-methoxybenzylidene)-4-thiazolidinon-2-ylidene>hydrazinoquinoline (128348-93-6)

Guidance literature:

Multi-step reaction with 5 steps

1: 70 percent / toluene p-sulphonic acid / benzene / 5 h / Heating

2: 80 percent / hydrazine hydrate / 0.33 h / Heating

3: 60 percent / ethanol / 0.5 h / Ambient temperature

4: 50 percent / sodium acetate / ethanol / 0.33 h / Heating

5: 61 percent / triethylamine / dioxane; methanol / Heating

With sodium acetate; toluene-4-sulfonic acid; hydrazine hydrate; triethylamine; In 1,4-dioxane; methanol; ethanol; benzene;

DOI:10.1002/ardp.19903230414

Reference yield:

2-chloro-3-[1,3-dioxolan-2-yl]-quinoline (128348-73-2) → 3-(1,3-dioxolan-2-yl)-2-<3-p-tolyl-5-(4-hydroxy-3-methoxybenzylidene)-4-thiazolidinon-2-ylidene>hydrazinoquinoline (128348-93-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 80 percent / hydrazine hydrate / 0.33 h / Heating

2: 60 percent / ethanol / 0.5 h / Ambient temperature

3: 50 percent / sodium acetate / ethanol / 0.33 h / Heating

4: 61 percent / triethylamine / dioxane; methanol / Heating

With sodium acetate; hydrazine hydrate; triethylamine; In 1,4-dioxane; methanol; ethanol;

DOI:10.1002/ardp.19903230414

Reference yield:

1-(3-(1,3-dioxolan-2-yl)quinolin-2-yl)hydrazine (128348-74-3) → 3-(1,3-dioxolan-2-yl)-2-<3-p-tolyl-5-(4-hydroxy-3-methoxybenzylidene)-4-thiazolidinon-2-ylidene>hydrazinoquinoline (128348-93-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 60 percent / ethanol / 0.5 h / Ambient temperature

2: 50 percent / sodium acetate / ethanol / 0.33 h / Heating

3: 61 percent / triethylamine / dioxane; methanol / Heating

With sodium acetate; triethylamine; In 1,4-dioxane; methanol; ethanol;

DOI:10.1002/ardp.19903230414

upstream raw materials:

2-chloro-3-quinoline carboxaldehyde

2-chloro-3-[1,3-dioxolan-2-yl]-quinoline

1-(3-(1,3-dioxolan-2-yl)quinolin-2-yl)hydrazine

C₂₀H₂₀N₄O₂S

Refernces