(R)-3-Hydroxy-4-oxo-β-jonon

Base Information

• Chemical Name: (R)-3-Hydroxy-4-oxo-β-jonon
• CAS No.: 80779-52-8
• Molecular Formula: C₁₃H₁₈O₃
• Molecular Weight: 222.284
• Mol file: 80779-52-8.mol

Synonyms:

Chemical Property of (R)-3-Hydroxy-4-oxo-β-jonon

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-3-Hydroxy-4-oxo-β-jonon

There total 9 articles about (R)-3-Hydroxy-4-oxo-β-jonon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-3,5,5-trimethyl-2-oxo-4-(3-oxobut-1-en-1-yl)cyclohex-3-en-1-yl acetate (74285-59-9) → (R)-3-Hydroxy-4-oxo-β-jonon (80779-52-8)

Guidance literature:

With Bacillus sp; sterilized food; In dimethyl sulfoxide; at 28 ℃; for 53h; pH 7.1;

DOI:10.1002/hlca.19810640750

Reference yield:

(E)-3,5,5-trimethyl-2-oxo-4-(3-oxobut-1-en-1-yl)cyclohex-3-en-1-yl acetate (74285-59-9) → (R)-3-Hydroxy-4-oxo-β-jonon (80779-52-8) + (S)-3-Acetoxy-4-oxo-β-jonon (74311-42-5)

Guidance literature:

With Bacillus sp; In dimethyl sulfoxide; at 28 ℃; for 53h; pH 7.1;

DOI:10.1002/hlca.19810640750

Reference yield:

(E)-β-ionone (79-77-6,14901-07-6) → (R)-3-Hydroxy-4-oxo-β-jonon (80779-52-8)

Guidance literature:

Multi-step reaction with 7 steps

1: 52 percent / pyridinium chlorochromate / dimethylsulfoxide / 5 h / 105 °C

2: 52 percent / triethyl orthoformate, p-toluenesulfonic acid / 0.5 h / oxo-β-ionone:ethylene glycol:triethyl orthoformate=1:1.5:1.2

3: toluene / 8 h / Heating

4: 1N HCl / methanol / 3 h

5: 85 percent / 1N NaOH / methanol / 0.5 h

6: 14.1 percent Chromat_. / pyridine / 2 h

7: 1N NaOH / methanol

With hydrogenchloride; sodium hydroxide; toluene-4-sulfonic acid; orthoformic acid triethyl ester; pyridinium chlorochromate; In pyridine; methanol; dimethyl sulfoxide; toluene;

DOI:10.1002/hlca.19810640750

upstream raw materials:

(E)-3,5,5-trimethyl-2-oxo-4-(3-oxobut-1-en-1-yl)cyclohex-3-en-1-yl acetate

(E)-β-ionone

(E)-2,4,4-trimethyl-3-(3-oxobut-1-en-1-yl)cyclohex-2-enone

4-Oxo-β-jonon-9-(aethylenacetal)