10-epi(+/-)ginkgolide A

Base Information

• Chemical Name: 10-epi(+/-)ginkgolide A
• CAS No.: 119460-49-0
• Molecular Formula: C₂₀H₂₄O₉
• Molecular Weight: 408.405
• Mol file: 119460-49-0.mol

Synonyms:

Chemical Property of 10-epi(+/-)ginkgolide A

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-epi(+/-)ginkgolide A

There total 12 articles about 10-epi(+/-)ginkgolide A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Ginkgolid A (15291-75-5,119460-49-0,119502-58-8,148683-79-8)

Guidance literature:

aus einem Gemisch v. Esterhemiacetal (Ib) u. Esteraldehyd (IIc)/ Me., h*ν;

DOI:10.1039/C29690001469

Reference yield:

C22H28O10 (119460-51-4) → ginkgolide A (15291-75-5,119460-49-0,119502-58-8,148683-79-8)

Guidance literature:

With boron trifluoride diethyl etherate; thiophenol; In dichloromethane; at -10 ℃; for 1h;

DOI:10.1016/0040-4039(88)85122-0

Reference yield:

C20H24O8 (112574-07-9) → ginkgolide A (15291-75-5,119460-49-0,119502-58-8,148683-79-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 84 percent / toluene; pyridine / 12 h / 45 °C

2: 90 percent / tri-n-butyltin hydride / dioxane / 3 h / Heating

3: 1.) osmium tetroxide, pyridine, 2.) excess iodine, calcium carbonate / 1.) 60 deg C, 24 h., 2.) CH₃OH-H₂O (10:1), 23 deg C, 12 h.

4: 1.) benzeneselenic anhydride, pyridine, 2.)sodium borohydride / 1.) anhydrous chlorobenzene, 80 deg C, 2 h., 2.) ethanol, -45 deg C, 15 min.

With pyridine; sodium tetrahydroborate; osmium(VIII) oxide; benzeneseleninic anhydride; iodine; tri-n-butyl-tin hydride; calcium carbonate; In 1,4-dioxane; pyridine; toluene;

DOI:10.1016/0040-4039(88)85122-0

upstream raw materials:

C₂₂H₂₈O₁₀

10-epi(+/-)ginkgolide A

C₂₀H₂₄O₇

C₂₀H₂₄O₈

Downstream raw materials:

ginkgolide A