Technology Process of N-(2,6-Dimethyl-phenyl)-2-(2-methyl-4-oxo-3,5,7,8-tetrahydro-4H-pyrido[4,3-d]pyrimidin-6-yl)-acetamide
There total 6 articles about N-(2,6-Dimethyl-phenyl)-2-(2-methyl-4-oxo-3,5,7,8-tetrahydro-4H-pyrido[4,3-d]pyrimidin-6-yl)-acetamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium methoxide / 3 h / 100 °C / in xylene or toluene
2: 92 percent / hydrogen / 10 percent Pd/C / aq. acetic acid
3: sodium ethoxide / ethanol / 12 h / 100 °C
4: sodium carbonate, sodium iodide / various solvent(s) / 12 h / 120 °C
With
hydrogen; sodium methylate; sodium ethanolate; sodium carbonate; sodium iodide;
palladium on activated charcoal;
In
ethanol; acetic acid;
DOI:10.1002/jhet.5570270708
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 92 percent / hydrogen / 10 percent Pd/C / aq. acetic acid
2: sodium ethoxide / ethanol / 12 h / 100 °C
3: sodium carbonate, sodium iodide / various solvent(s) / 12 h / 120 °C
With
hydrogen; sodium ethanolate; sodium carbonate; sodium iodide;
palladium on activated charcoal;
In
ethanol; acetic acid;
DOI:10.1002/jhet.5570270708
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogen / 10 percent Pd/C / aq. acetic acid / 50 °C
2: sodium carbonate, sodium iodide / various solvent(s) / 12 h / 120 °C
With
hydrogen; sodium carbonate; sodium iodide;
palladium on activated charcoal;
In
acetic acid;
DOI:10.1002/jhet.5570270708