N-Nitroso-N-phenylglycine

Base Information

• Chemical Name: N-Nitroso-N-phenylglycine
• CAS No.: 78786-56-8
• Molecular Formula: C₁₁H₁₀N₄O₃
• Molecular Weight: 246.225
• Mol file: 78786-56-8.mol

Synonyms:

Chemical Property of N-Nitroso-N-phenylglycine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Nitroso-N-phenylglycine

There total 3 articles about N-Nitroso-N-phenylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2-Pyrazol-1-yl-phenylamino)-acetic acid ethyl ester → N-Nitroso-N-phenylglycine (78786-56-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 10 percent aq. NaOH / ethanol

2: NaNO₂, 25 percent aq. HCl / 3 h

With hydrogenchloride; sodium hydroxide; sodium nitrite; In ethanol;

DOI:10.1002/ardp.19813140605

Reference yield:

2-(1H-pyrazol-1-yl)aniline (54705-91-8) → N-Nitroso-N-phenylglycine (78786-56-8)

Guidance literature:

Multi-step reaction with 3 steps

1: aq. sodium acetate / ethanol / 40 h / 130 °C

2: 10 percent aq. NaOH / ethanol

3: NaNO₂, 25 percent aq. HCl / 3 h

With hydrogenchloride; sodium hydroxide; sodium acetate; sodium nitrite; In ethanol;

DOI:10.1002/ardp.19813140605

Reference yield:

N-phenylglycine (78786-55-7) → N-Nitroso-N-phenylglycine (78786-56-8)

Guidance literature:

With hydrogenchloride; sodium nitrite; for 3h; Yield given;

DOI:10.1002/ardp.19813140605

upstream raw materials:

N-phenylglycine

2-(1H-pyrazol-1-yl)aniline

Downstream raw materials:

3-sydnone

Refernces