hesperetin 7-O-β-D-glucuronide

Base Information

Chemical Name:hesperetin 7-O-β-D-glucuronide
CAS No.:67322-08-1
Molecular Formula:C₂₂H₂₂O₁₂
Molecular Weight:478.409
Hs Code.:

Synonyms:

Suppliers and Price of hesperetin 7-O-β-D-glucuronide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
Hesperetin7-O-β-D-Glucuronide
50 mg
$ 2200.00

Total 4 raw suppliers

Chemical Property of hesperetin 7-O-β-D-glucuronide

Chemical Property:

Melting Point:189-192°C (dec.)
Boiling Point:856.5±65.0 °C(Predicted)
PKA:2.74±0.70(Predicted)
Density:1.651±0.06 g/cm3(Predicted)
Storage Temp.:Hygroscopic, Refrigerator, Under Inert Atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

Hesperetin7-O-β-D-Glucuronide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses A metabolite of Hesperetin , the main circulating metabolite involved in osteoblast differentiation. A metabolite of Hesperetin (H289500), the main circulating metabolite involved in osteoblast differentiation.

Technology Process of hesperetin 7-O-β-D-glucuronide

There total 5 articles about hesperetin 7-O-β-D-glucuronide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 1237479-03-6
3',5-di-O-benzoylhesperetin 7-O-[methyl (2'',3'',4''-tri-O-acetyl)-β-D-glucopyranosyl uronate]

: 67322-08-1
hesperetin 7-O-β-D-glucuronide

Guidance literature:: 3',5-di-O-benzoylhesperetin 7-O-[methyl (2'',3'',4''-tri-O-acetyl)-β-D-glucopyranosyl uronate]; With water; sodium carbonate; at 0 - 20 ℃; for 5h; Inert atmosphere;

In water; pH=Ca. 6; Inert atmosphere;
DOI:10.1021/jf1010403

Reference yield:

: 3',5-di-O-benzoylhesperetin

: 67322-08-1
hesperetin 7-O-β-D-glucuronide

Guidance literature:: Multi-step reaction with 2 steps

1.1: boron trifluoride diethyl etherate / dichloromethane / 20 °C / Molecular sieve; Inert atmosphere; Cooling with ice

2.1: water; sodium carbonate / 5 h / 0 - 20 °C / Inert atmosphere

2.2: Dowex 50WX₄-50 H(+) form / pH Ca_. 6 / Inert atmosphere

With boron trifluoride diethyl etherate; water; sodium carbonate; In dichloromethane;
DOI:10.1021/jf1010403

Reference yield:

: 520-33-2,41001-90-5,69097-99-0
(S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone

: 67322-08-1
hesperetin 7-O-β-D-glucuronide

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine / tetrahydrofuran / 20 °C / Cooling with ice

2.1: 1H-imidazole; thiophenol / 1-methyl-pyrrolidin-2-one / 0 - 20 °C

3.1: boron trifluoride diethyl etherate / dichloromethane / 20 °C / Molecular sieve; Inert atmosphere; Cooling with ice

4.1: water; sodium carbonate / 5 h / 0 - 20 °C / Inert atmosphere

4.2: Dowex 50WX₄-50 H(+) form / pH Ca_. 6 / Inert atmosphere

With 1H-imidazole; boron trifluoride diethyl etherate; water; sodium carbonate; thiophenol; triethylamine; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; dichloromethane;
DOI:10.1021/jf1010403