3(2H)-furanone, 5-hydroxy-4-[(2S)-2-[(1S,2S,6R)-2-[(1E)-3-hydroxy-2-[(2R,3R)-tetrahydro-3-methyl-6-[(1E,3S)-3-[(2R,3S,5R)-tetrahydro-5-[(1S)-1-methoxyethyl]-3-methyl-2-furanyl]-1-butenyl]-2H-pyran-2-yl]-1-propenyl]-6-methylcyclohexyl]-1-oxopropyl]-, monos

Base Information

Chemical Name:3(2H)-furanone, 5-hydroxy-4-[(2S)-2-[(1S,2S,6R)-2-[(1E)-3-hydroxy-2-[(2R,3R)-tetrahydro-3-methyl-6-[(1E,3S)-3-[(2R,3S,5R)-tetrahydro-5-[(1S)-1-methoxyethyl]-3-methyl-2-furanyl]-1-butenyl]-2H-pyran-2-yl]-1-propenyl]-6-methylcyclohexyl]-1-oxopropyl]-, monos
CAS No.:149298-89-5
Molecular Formula:C₃₅H₅₃O₈*Na
Molecular Weight:624.791
Hs Code.:

3(2H)-furanone, 5-hydroxy-4-[(2S)-2-[(1S,2S,6R)-2-[(1E)-3-hydroxy-2-[(2R,3R)-tetrahydro-3-methyl-6-[(1E,3S)-3-[(2R,3S,5R)-tetrahydro-5-[(1S)-1-methoxyethyl]-3-methyl-2-furanyl]-1-butenyl]-2H-pyran-2-yl]-1-propenyl]-6-methylcyclohexyl]-1-oxopropyl]-, monos

Synonyms:

Suppliers and Price of 3(2H)-furanone, 5-hydroxy-4-[(2S)-2-[(1S,2S,6R)-2-[(1E)-3-hydroxy-2-[(2R,3R)-tetrahydro-3-methyl-6-[(1E,3S)-3-[(2R,3S,5R)-tetrahydro-5-[(1S)-1-methoxyethyl]-3-methyl-2-furanyl]-1-butenyl]-2H-pyran-2-yl]-1-propenyl]-6-methylcyclohexyl]-1-oxopropyl]-, monos

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Chemical Property of 3(2H)-furanone, 5-hydroxy-4-[(2S)-2-[(1S,2S,6R)-2-[(1E)-3-hydroxy-2-[(2R,3R)-tetrahydro-3-methyl-6-[(1E,3S)-3-[(2R,3S,5R)-tetrahydro-5-[(1S)-1-methoxyethyl]-3-methyl-2-furanyl]-1-butenyl]-2H-pyran-2-yl]-1-propenyl]-6-methylcyclohexyl]-1-oxopropyl]-, monos

Chemical Property:

Vapor Pressure:4.49E-22mmHg at 25°C

Purity/Quality:

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Hazard Codes:

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Useful:

Technology Process of 3(2H)-furanone, 5-hydroxy-4-[(2S)-2-[(1S,2S,6R)-2-[(1E)-3-hydroxy-2-[(2R,3R)-tetrahydro-3-methyl-6-[(1E,3S)-3-[(2R,3S,5R)-tetrahydro-5-[(1S)-1-methoxyethyl]-3-methyl-2-furanyl]-1-butenyl]-2H-pyran-2-yl]-1-propenyl]-6-methylcyclohexyl]-1-oxopropyl]-, monos

There total 29 articles about 3(2H)-furanone, 5-hydroxy-4-[(2S)-2-[(1S,2S,6R)-2-[(1E)-3-hydroxy-2-[(2R,3R)-tetrahydro-3-methyl-6-[(1E,3S)-3-[(2R,3S,5R)-tetrahydro-5-[(1S)-1-methoxyethyl]-3-methyl-2-furanyl]-1-butenyl]-2H-pyran-2-yl]-1-propenyl]-6-methylcyclohexyl]-1-oxopropyl]-, monos which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 130517-70-3
(S)-2-((1R,2S,6R)-2-Formyl-6-methyl-cyclohexyl)-propionitrile

: 149298-89-5
tetronasin sodium salt

Guidance literature:: Multi-step reaction with 8 steps

1: 1.) LDA / 1.) THF, -100 deg C, 2.) -95 deg C, 30 min

2: pyridine, DMAP

3: DBU / Ambient temperature

4: 34 percent / acetone / 0 °C / Irradiation

5: (i-Bu)2AlH (DIBALH) / toluene

6: imidazole

7: 80 percent / ZrCl₄ / CH₂Cl₂ / 0.25 h / 0 °C

8: 1.) n-Bu₄NF (TBAF), 2.) HF / 1.) THF, 2.) CH₃CN

With pyridine; 1H-imidazole; dmap; hydrogen fluoride; tetrabutyl ammonium fluoride; diisobutylaluminium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium diisopropyl amide; zirconium(IV) chloride; In dichloromethane; acetone; toluene;
DOI:10.1016/S0040-4039(00)60377-5

Reference yield:

: 130258-65-0
Methanesulfonic acid (1R,3S)-1-[(S)-1-(tert-butyl-diphenyl-silanyloxy)-ethyl]-3-methyl-4-oxo-butyl ester

: 149298-89-5
tetronasin sodium salt

Guidance literature:: Multi-step reaction with 22 steps

1: toluene / -75 °C

2: n-Bu₄NF (TBAF) / tetrahydrofuran / r.t. to 50 deg C

3: 83 percent / NaH

4: O₃

5: NaBH₄

6: Bu₃P, pyridine

7: mcpba / CH₂Cl₂

8: 1.) n-BuLi / 1.) THF

9: NaN(TMS)2

10: AIBN / toluene

11: (i-Bu)2AlH (DIBALH)

12: DMSO, (COCl)2, Et₃N / CH₂Cl₂

13: NaClO₂

15: 1.) LDA / 1.) THF, -100 deg C, 2.) -95 deg C, 30 min

16: pyridine, DMAP

17: DBU / Ambient temperature

18: 34 percent / acetone / 0 °C / Irradiation

19: (i-Bu)2AlH (DIBALH) / toluene

20: imidazole

21: 80 percent / ZrCl₄ / CH₂Cl₂ / 0.25 h / 0 °C

22: 1.) n-Bu₄NF (TBAF), 2.) HF / 1.) THF, 2.) CH₃CN

With pyridine; 1H-imidazole; dmap; sodium chlorite; sodium tetrahydroborate; n-butyllithium; oxalyl dichloride; 2,2'-azobis(isobutyronitrile); tributylphosphine; hydrogen fluoride; tetrabutyl ammonium fluoride; sodium hexamethyldisilazane; sodium hydride; diisobutylaluminium hydride; ozone; dimethyl sulfoxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide; zirconium(IV) chloride; In tetrahydrofuran; dichloromethane; acetone; toluene;
DOI:10.1016/S0040-4039(00)60377-5

Reference yield:

: 131507-74-9
(2R,3S,5R)-2-((R)-2-Benzenesulfonyl-1-methyl-ethyl)-5-((S)-1-methoxy-ethyl)-3-methyl-tetrahydro-furan

: 149298-89-5
tetronasin sodium salt

Guidance literature:: Multi-step reaction with 15 steps

1: 1.) n-BuLi / 1.) THF

2: NaN(TMS)2

3: AIBN / toluene

4: (i-Bu)2AlH (DIBALH)

5: DMSO, (COCl)2, Et₃N / CH₂Cl₂

6: NaClO₂

8: 1.) LDA / 1.) THF, -100 deg C, 2.) -95 deg C, 30 min

9: pyridine, DMAP

10: DBU / Ambient temperature

11: 34 percent / acetone / 0 °C / Irradiation

12: (i-Bu)2AlH (DIBALH) / toluene

13: imidazole

14: 80 percent / ZrCl₄ / CH₂Cl₂ / 0.25 h / 0 °C

15: 1.) n-Bu₄NF (TBAF), 2.) HF / 1.) THF, 2.) CH₃CN

With pyridine; 1H-imidazole; dmap; sodium chlorite; n-butyllithium; oxalyl dichloride; 2,2'-azobis(isobutyronitrile); hydrogen fluoride; tetrabutyl ammonium fluoride; sodium hexamethyldisilazane; diisobutylaluminium hydride; dimethyl sulfoxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; lithium diisopropyl amide; zirconium(IV) chloride; In dichloromethane; acetone; toluene;
DOI:10.1016/S0040-4039(00)60377-5