(S)-2-Fluoro-hexanoic acid 4-(5-dodecyl-pyrimidin-2-yl)-phenyl ester

Base Information

Chemical Name:(S)-2-Fluoro-hexanoic acid 4-(5-dodecyl-pyrimidin-2-yl)-phenyl ester
CAS No.:129832-82-2
Molecular Formula:C₂₈H₄₁FN₂O₂
Molecular Weight:456.644
Hs Code.:

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Chemical Property of (S)-2-Fluoro-hexanoic acid 4-(5-dodecyl-pyrimidin-2-yl)-phenyl ester

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Technology Process of (S)-2-Fluoro-hexanoic acid 4-(5-dodecyl-pyrimidin-2-yl)-phenyl ester

There total 4 articles about (S)-2-Fluoro-hexanoic acid 4-(5-dodecyl-pyrimidin-2-yl)-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 127608-47-3
(2S)-2-fluorohexan-1-ol

: 129832-82-2
(S)-2-Fluoro-hexanoic acid 4-(5-dodecyl-pyrimidin-2-yl)-phenyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 70 percent / sodium acetate / benzene / 90 °C

2: 62 percent / 16 M nitric acid / acetic acid / 55 - 60 °C

3: thionyl chloride / 90 °C

4: 1.) triethylenediamine, 2.) sodium hydride / 1.) benzene, 50 deg C, 2.) 90 deg C

With 1,4-diaza-bicyclo[2.2.2]octane; thionyl chloride; nitric acid; sodium acetate; sodium hydride; In acetic acid; benzene;

Reference yield:

: 129832-70-8
Acetic acid (S)-2-fluoro-hexyl ester

: 129832-82-2
(S)-2-Fluoro-hexanoic acid 4-(5-dodecyl-pyrimidin-2-yl)-phenyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 62 percent / 16 M nitric acid / acetic acid / 55 - 60 °C

2: thionyl chloride / 90 °C

3: 1.) triethylenediamine, 2.) sodium hydride / 1.) benzene, 50 deg C, 2.) 90 deg C

With 1,4-diaza-bicyclo[2.2.2]octane; thionyl chloride; nitric acid; sodium hydride; In acetic acid;

Reference yield:

: 113776-26-4
(S)-(-)-2-fluorohexanoic acid

: 129832-82-2
(S)-2-Fluoro-hexanoic acid 4-(5-dodecyl-pyrimidin-2-yl)-phenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / 90 °C

2: 1.) triethylenediamine, 2.) sodium hydride / 1.) benzene, 50 deg C, 2.) 90 deg C

With 1,4-diaza-bicyclo[2.2.2]octane; thionyl chloride; sodium hydride;