2,2,4,4-Tetramethyltetrahydrofuran

Base Information

• Chemical Name: 2,2,4,4-Tetramethyltetrahydrofuran
• CAS No.: 3358-28-9
• Molecular Formula: C8H16O
• Molecular Weight: 128.214
• Hs Code.: 2932190090
• DSSTox Substance ID: DTXSID10187275
• Nikkaji Number: J27.219A
• Wikidata: Q83058915
• Mol file: 3358-28-9.mol

Synonyms:2,2,4,4-Tetramethyltetrahydrofuran;3358-28-9;2,2,4,4-tetramethyloxolane;Furan, tetrahydro-2,2,4,4-tetramethyl-;SCHEMBL673997;DTXSID10187275;FIDGQQIVMWAIAD-UHFFFAOYSA-N;AKOS006281471;(4-Aminopyridin-3-yl)(phenyl)methanone;Tetrahydrofuran, 2,2,4,4-tetramethyl-;AS-61642;FT-0709577;D93046

Chemical Property of 2,2,4,4-Tetramethyltetrahydrofuran

Chemical Property:

• Vapor Pressure: 17.8mmHg at 25°C
• Refractive Index: 1.408
• Boiling Point: 121.1 °C at 760 mmHg
• Flash Point: 24.3 °C
• PSA: 9.23000
• Density: 0.818 g/cm³
• LogP: 2.21150
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 128.120115130
• Heavy Atom Count: 9
• Complexity: 114

Purity/Quality:

99%, ^*data from raw suppliers

2,2,4,4-TETRAMETHYLTETRAHYDROFURAN 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CC(OC1)(C)C)C

Technology Process of 2,2,4,4-Tetramethyltetrahydrofuran

There total 15 articles about 2,2,4,4-Tetramethyltetrahydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2,4-trimethylpentane-1,4-diol (80864-10-4) → 2,2,4,4-Tetramethyltetrahydrofuran (3358-28-9)

Guidance literature:

With water; at 180 ℃; im Druckrohr;

Reference yield:

→ 2,2,4,4-Tetramethyltetrahydrofuran (3358-28-9)

Guidance literature:

With sulfuric acid; at 160 ℃; im Druckrohr;

Reference yield:

2,2,4-trimethylpentane (540-84-1) → 2,2,4,4-Tetramethyltetrahydrofuran (3358-28-9) + 2-tert.-Butyl-3-methyl-oxetan (7045-82-1)

Guidance literature:

at 400 ℃; under 2574.3 Torr;

DOI:10.1021/ja01633a037 DOI:10.1021/ie51394a030

upstream raw materials:

2,2,4-trimethylpentane-1,4-diol

2,2,4-trimethylpentan-1,3-diol

triethyl phosphate

benzene

Refernces

• 1、 Lischke, G.,Oehlmann, G.. "Untersuchungen zur Kinetik und zum Mechanismus der Isooctanoxydation". . p. 555 - 572. Retrieved 2007/10/02.