(5R,6R)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-5,6-dimethyl-tetrahydro-pyran-2-one

Base Information

Chemical Name:(5R,6R)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-5,6-dimethyl-tetrahydro-pyran-2-one
CAS No.:120093-61-0
Molecular Formula:C₂₄H₃₂O₃Si
Molecular Weight:396.602
Hs Code.:

Synonyms:

Suppliers and Price of (5R,6R)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-5,6-dimethyl-tetrahydro-pyran-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (5R,6R)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-5,6-dimethyl-tetrahydro-pyran-2-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (5R,6R)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-5,6-dimethyl-tetrahydro-pyran-2-one

There total 13 articles about (5R,6R)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-5,6-dimethyl-tetrahydro-pyran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2385-77-5
(R)-Citronellal

: 120093-61-0
(5R,6R)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-5,6-dimethyl-tetrahydro-pyran-2-one

Guidance literature:: Multi-step reaction with 12 steps

1: LDA / tetrahydrofuran

2: methanol

3: aq. NaHCO₃ / CH₂Cl₂

4: 95 percent / NaBH₄, CeCl₃ / methanol

5: cumene hydroperoxide / diisopropyl (+)-tartrate, Ti(i-OPr)4

6: 90 percent / imidazole

7: O₃ / CHCl₃ / -78 °C

8: CrO₃, H₂SO₄ / acetone / 0 °C

10: 50 percent / CF₃COOH / CHCl₃ / -10 °C

11: 90 percent / Ph₃P, I₂, imidazole / benzene

12: n-Bu₃SnH, AIBN

With 1H-imidazole; chromium(VI) oxide; sodium tetrahydroborate; cerium(III) chloride; 2,2'-azobis(isobutyronitrile); Cumene hydroperoxide; sulfuric acid; iodine; tri-n-butyl-tin hydride; sodium hydrogencarbonate; ozone; triphenylphosphine; trifluoroacetic acid; lithium diisopropyl amide; titanium(IV) isopropylate; L-(+)-diisopropyl tartrate; In tetrahydrofuran; methanol; dichloromethane; chloroform; acetone; benzene;
DOI:10.1016/S0040-4039(00)86693-9

Reference yield:

: 1117-61-9
(3R)-citronellol

: 120093-61-0
(5R,6R)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-5,6-dimethyl-tetrahydro-pyran-2-one

Guidance literature:: Multi-step reaction with 13 steps

1: 70 percent / pyridinium chlorochromate / CH₂Cl₂

2: LDA / tetrahydrofuran

3: methanol

4: aq. NaHCO₃ / CH₂Cl₂

5: 95 percent / NaBH₄, CeCl₃ / methanol

6: cumene hydroperoxide / diisopropyl (+)-tartrate, Ti(i-OPr)4

7: 90 percent / imidazole

8: O₃ / CHCl₃ / -78 °C

9: CrO₃, H₂SO₄ / acetone / 0 °C

11: 50 percent / CF₃COOH / CHCl₃ / -10 °C

12: 90 percent / Ph₃P, I₂, imidazole / benzene

13: n-Bu₃SnH, AIBN

With 1H-imidazole; chromium(VI) oxide; sodium tetrahydroborate; cerium(III) chloride; 2,2'-azobis(isobutyronitrile); Cumene hydroperoxide; sulfuric acid; iodine; tri-n-butyl-tin hydride; sodium hydrogencarbonate; ozone; triphenylphosphine; pyridinium chlorochromate; trifluoroacetic acid; lithium diisopropyl amide; titanium(IV) isopropylate; L-(+)-diisopropyl tartrate; In tetrahydrofuran; methanol; dichloromethane; chloroform; acetone; benzene;
DOI:10.1016/S0040-4039(00)86693-9

Reference yield:

: 120093-49-4
(3R)-α-methylene-3,7-dimethyl-6-octen-1-al

: 120093-61-0
(5R,6R)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-5,6-dimethyl-tetrahydro-pyran-2-one

Guidance literature:: Multi-step reaction with 9 steps

1: 95 percent / NaBH₄, CeCl₃ / methanol

2: cumene hydroperoxide / diisopropyl (+)-tartrate, Ti(i-OPr)4

3: 90 percent / imidazole

4: O₃ / CHCl₃ / -78 °C

5: CrO₃, H₂SO₄ / acetone / 0 °C

7: 50 percent / CF₃COOH / CHCl₃ / -10 °C

8: 90 percent / Ph₃P, I₂, imidazole / benzene

9: n-Bu₃SnH, AIBN

With 1H-imidazole; chromium(VI) oxide; sodium tetrahydroborate; cerium(III) chloride; 2,2'-azobis(isobutyronitrile); Cumene hydroperoxide; sulfuric acid; iodine; tri-n-butyl-tin hydride; ozone; triphenylphosphine; trifluoroacetic acid; titanium(IV) isopropylate; L-(+)-diisopropyl tartrate; In methanol; chloroform; acetone; benzene;
DOI:10.1016/S0040-4039(00)86693-9