{(2R,3S)-2-(2-Allyloxycarbonylamino-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-3-[(R)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester

Base Information

• Chemical Name: {(2R,3S)-2-(2-Allyloxycarbonylamino-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-3-[(R)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester
• CAS No.: 80575-18-4
• Molecular Formula: C₃₈H₃₈Cl₃N₂O₈PS₃
• Molecular Weight: 884.259

Synonyms:

Chemical Property of {(2R,3S)-2-(2-Allyloxycarbonylamino-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-3-[(R)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {(2R,3S)-2-(2-Allyloxycarbonylamino-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-3-[(R)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester

There total 18 articles about {(2R,3S)-2-(2-Allyloxycarbonylamino-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-3-[(R)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-<(allyloxy)carbonyl>cysteamine (135920-21-7) → {(2R,3S)-2-(2-Allyloxycarbonylamino-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-3-[(S)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ5-phosphanylidene)-acetic acid allyl ester (80575-18-4,80629-71-6)

Guidance literature:

Multi-step reaction with 5 steps

1: KOH

3: benzene / 80 °C

4: Et₃N

5: dimethylformamide

With potassium hydroxide; triethylamine; In N,N-dimethyl-formamide; benzene;

DOI:10.1016/S0040-4039(01)81939-0

Reference yield:

N-<(allyloxy)carbonyl>cysteamine (135920-21-7) → {(2R,3S)-2-(2-Allyloxycarbonylamino-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-3-[(R)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ5-phosphanylidene)-acetic acid allyl ester (80575-18-4,80629-71-6)

Guidance literature:

Multi-step reaction with 5 steps

1: KOH

3: benzene / 80 °C

4: Et₃N

5: dimethylformamide

With potassium hydroxide; triethylamine; In N,N-dimethyl-formamide; benzene;

DOI:10.1016/S0040-4039(01)81939-0

Reference yield:

1-(t-butyldimethylsilyl)-3-(1-hydroxyethyl)-4-ethylthioazetidin-2-one (76431-27-1) → {(2R,3S)-2-(2-Allyloxycarbonylamino-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-3-[(S)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ5-phosphanylidene)-acetic acid allyl ester (80575-18-4,80629-71-6)

Guidance literature:

Multi-step reaction with 7 steps

1: pyridine

2: acidic desilylation

3: Cl₂ / -20 °C

5: benzene / 80 °C

6: Et₃N

7: dimethylformamide

With pyridine; chlorine; triethylamine; In N,N-dimethyl-formamide; benzene;

DOI:10.1016/S0040-4039(01)81939-0

upstream raw materials:

triphenylphosphine

N-<(allyloxy)carbonyl>cysteamine

1-(t-butyldimethylsilyl)-3-(1-hydroxyethyl)-4-ethylthioazetidin-2-one

Carbonic acid 1-(2-ethylsulfanyl-4-oxo-azetidin-3-yl)-ethyl ester 2,2,2-trichloro-ethyl ester

Downstream raw materials:

(5R,6S)-3-(2-Amino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid

(5R,6R)-3-(2-Amino-ethylsulfanyl)-6-((S)-1-hydroxy-ethyl)-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid

(5R,6S)-3-(2-Amino-ethylsulfanyl)-6-((S)-1-hydroxy-ethyl)-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 80575-18-4 {(2R,3S)-2-(2-Allyloxycarbonylamino-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-3-[(R)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send