C₁₆H₄⁽²⁾H₉N

Base Information

• Chemical Name: C₁₆H₄⁽²⁾H₉N
• CAS No.: 1619225-24-9
• Molecular Formula: C₁₆H₁₃N
• Molecular Weight: 228.214
• Mol file: 1619225-24-9.mol

Synonyms:

Chemical Property of C₁₆H₄⁽²⁾H₉N

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₄⁽²⁾H₉N

There total 3 articles about C₁₆H₄⁽²⁾H₉N which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetophenone-d5 (28077-64-7) → C16H4(2)H9N (1619225-24-9)

Guidance literature:

Multi-step reaction with 3 steps

1: hydroxylamine hydrochloride; potassium acetate / methanol / 0.67 h / Reflux

2: triethylamine / dichloromethane / 0.5 h / 0 - 20 °C

3: palladium diacetate / toluene / 24 h / 150 °C / Sealed tube; Inert atmosphere

With hydroxylamine hydrochloride; potassium acetate; palladium diacetate; triethylamine; In methanol; dichloromethane; toluene;

DOI:10.1021/jo5010586

Reference yield:

acetophenone oxime-d5 → C16H4(2)H9N (1619225-24-9)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 0.5 h / 0 - 20 °C

2: palladium diacetate / toluene / 24 h / 150 °C / Sealed tube; Inert atmosphere

With palladium diacetate; triethylamine; In dichloromethane; toluene;

DOI:10.1021/jo5010586

Reference yield:

1-(phenyl-d5)ethan-1-one O-pivaloyl oxime (1619225-22-7) → C16H4(2)H9N (1619225-24-9)

Guidance literature:

With palladium diacetate; In toluene; at 150 ℃; for 24h; regioselective reaction; Kinetics; Sealed tube; Inert atmosphere;

DOI:10.1021/jo5010586

upstream raw materials:

1-(phenyl-d₅)ethan-1-one O-pivaloyl oxime

acetophenone-d5

Refernces