benzofurazan-4-carboxylic acid

Base Information

• Chemical Name: benzofurazan-4-carboxylic acid
• CAS No.: 32863-21-1
• Molecular Formula: C₇H₄N₂O₃
• Molecular Weight: 164.12
• Mol file: 32863-21-1.mol

Synonyms:

Chemical Property of benzofurazan-4-carboxylic acid

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

2,1,3-benzoxadiazole-4-carboxylicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,1,3-Benzoxadiazole-4-carboxylic Acid can be used as orexin receptor antagonists to treat various diseases.

Technology Process of benzofurazan-4-carboxylic acid

There total 2 articles about benzofurazan-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

benzo[c][1,2,5]oxadiazole-4-carbaldehyde (32863-32-4) → benzofurazan-4-carboxylic acid (32863-21-1)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; at 25 ℃; for 10h; Reagent/catalyst; Temperature; Solvent;

Reference yield:

→ benzofurazan-4-carboxylic acid (32863-21-1)

Guidance literature:

XVII, AgNO3;

Reference yield:

benzofurazan-4-carboxylic acid (32863-21-1) → benzo[1,2,5]oxadiazole-4-carbonyl chloride (111595-71-2)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; for 0.5h; Heating;

DOI:10.1016/S0014-827X(01)01139-9

upstream raw materials:

benzo[c][1,2,5]oxadiazole-4-carbaldehyde

Downstream raw materials:

benzo[1,2,5]oxadiazole-4-carbonyl chloride

benzofurazan-4-carboxylic acid methyl ester

4-benzofurazanylcarboxamide