1-(2-hydroxyethyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid

Base Information

Chemical Name:1-(2-hydroxyethyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid
CAS No.:1052561-82-6
Molecular Formula:C₈H₁₂N₂O₃
Molecular Weight:184.195
Hs Code.:
European Community (EC) Number:833-958-0

Synonyms:1-(2-hydroxyethyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid;1052561-82-6;1-(2-hydroxyethyl)-3,5-dimethylpyrazole-4-carboxylic acid;SCHEMBL19119188;AKOS000137492;MCULE-5343422715;CS-0248238;EN300-39458;Z234969411;1-(2-hydroxyethyl)-3,5-dimethyl-1H-pyrazole-4-carboxylicacid

Suppliers and Price of 1-(2-hydroxyethyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(2-HYDROXYETHYL)-3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID 95.00%
5G
$ 2181.31

American Custom Chemicals Corporation
1-(2-HYDROXYETHYL)-3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID 95.00%
2.5G
$ 1635.30

American Custom Chemicals Corporation
1-(2-HYDROXYETHYL)-3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID 95.00%
1G
$ 1070.84

AK Scientific
1-(2-Hydroxyethyl)-3,5-dimethyl-1H-pyrazole-4-carboxylicacid
1g
$ 831.00

AK Scientific
1-(2-Hydroxyethyl)-3,5-dimethyl-1H-pyrazole-4-carboxylicacid
100mg
$ 310.00

Total 4 raw suppliers

Chemical Property of 1-(2-hydroxyethyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid

Chemical Property:

XLogP3:-0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:184.08479225
Heavy Atom Count:13
Complexity:198

Purity/Quality:

97% ^*data from raw suppliers

1-(2-HYDROXYETHYL)-3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=NN1CCO)C)C(=O)O

Technology Process of 1-(2-hydroxyethyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid

There total 4 articles about 1-(2-hydroxyethyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 1610378-56-7
1-(2-acetoxyethyl)-3,5-dimethylpyrazole-4-carboxylic acid

: 1052561-82-6
1-(2-hydroxyethyl)-3,5-dimethylpyrazole-4-carboxylic acid

Guidance literature:: With sodium hydroxide; In water; at 20 ℃; for 3h;
DOI:10.1134/S1070363214040343

Reference yield:

: 1099772-09-4
1-(2-hydroxyethyl)-3,5-dimethyl-1H-pyrazole-4-carbaldehyde

: 1610378-54-5
1-carboxymethyl-3,5-dimethyl-1H-pyrazole-4-carboxylic acid

: 1052561-82-6
1-(2-hydroxyethyl)-3,5-dimethylpyrazole-4-carboxylic acid

Guidance literature:: With potassium permanganate; N-benzyl-N,N,N-triethylammonium chloride; In water; benzene; at 0 - 30 ℃;
DOI:10.1134/S1070363214040343

Reference yield:

: 67000-31-1
1-(2-acetoxyethyl)-3,5-dimethyl-1H-pyrazole

: 1052561-82-6
1-(2-hydroxyethyl)-3,5-dimethylpyrazole-4-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: trichlorophosphate

2: potassium permanganate; N-benzyl-N,N,N-triethylammonium chloride / water; benzene / 12 h / 20 - 30 °C

3: sodium hydroxide / water / 3 h / 20 °C

With potassium permanganate; N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide; trichlorophosphate; In water; benzene; 1: |Vilsmeier-Haack Formylation;
DOI:10.1134/S1070363214040343