Technology Process of (2R)-2,5-dimethyl-2-isopropylcyclohexanol
There total 2 articles about (2R)-2,5-dimethyl-2-isopropylcyclohexanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
diethyl ether;
for 42h;
Heating;
DOI:10.1021/jo00349a005
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 90 percent / H2 / 10percent Pd/C / ethanol / 760 Torr / Ambient temperature
2: 97 percent / LiAlH4 / diethyl ether / 42 h / Heating
With
lithium aluminium tetrahydride; hydrogen;
palladium on activated charcoal;
In
diethyl ether; ethanol;
DOI:10.1021/jo00349a005
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) NaNH2 / 1.) toluene, ether, reflux, 1.5 h, 2.) reflux, 3 h
2: 70 percent / 375 °C
3: 1.) potassium borohydride, aluminium chloride, 2.) H2O2, 3 N NaOH / 1.) diglyme, RT, 5 h, 2.) RT, 1.5 h
With
sodium hydroxide; aluminium trichloride; potassium borohydride; dihydrogen peroxide; sodium amide;
DOI:10.1021/jo00349a005
