7-bromo-7,8,9,10-tetrahydrobenzo[f]quinoline-9,10-diyl diacetate

Base Information

• Chemical Name: 7-bromo-7,8,9,10-tetrahydrobenzo[f]quinoline-9,10-diyl diacetate
• CAS No.: 103620-32-2
• Molecular Formula: C₁₇H₁₆BrNO₄
• Molecular Weight: 378.222
• Mol file: 103620-32-2.mol

Synonyms:

Chemical Property of 7-bromo-7,8,9,10-tetrahydrobenzo[f]quinoline-9,10-diyl diacetate

Chemical Property:

• Vapor Pressure: 2.54E-09mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-bromo-7,8,9,10-tetrahydrobenzo[f]quinoline-9,10-diyl diacetate

There total 2 articles about 7-bromo-7,8,9,10-tetrahydrobenzo[f]quinoline-9,10-diyl diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 7.2%

trans-9,10-diacetoxy-7,8,9,10-tetrahydrobenzoquinolines (103620-22-0) → trans-9,10-diacetoxy-7-bromo-7,8,9,10-tetrahydrobenzoquinoline (103620-32-2) + trans-9,10-diacetoxy-7,7-dibromo-7,8,9,10-tetrahydrobenzoquinoline (103620-31-1)

Guidance literature:

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; at 70 - 75 ℃; for 0.5h;

DOI:10.1021/jo00368a001

Reference yield:

7,8,9,10-tetrahydrobenzoquinoline (80028-83-7) → trans-9,10-diacetoxy-7-bromo-7,8,9,10-tetrahydrobenzoquinoline (103620-32-2)

Guidance literature:

Multi-step reaction with 2 steps

2: 52.4 percent / N-bromosuccinimide(NBS), α,α'-azobis(butyronitrile)(AIBN) / CCl4 / 0.5 h / 70 - 75 °C

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane;

DOI:10.1021/jo00368a001

upstream raw materials:

trans-9,10-diacetoxy-7,8,9,10-tetrahydrobenzoquinolines

7,8,9,10-tetrahydrobenzoquinoline

Refernces