Thymidine, 3'-amino-3'-deoxy-a-(phenylmethoxy)-

Base Information

Chemical Name:Thymidine, 3'-amino-3'-deoxy-a-(phenylmethoxy)-
CAS No.:137022-35-6
Molecular Formula:C17H21N3O5
Molecular Weight:347.36600
Hs Code.:

Synonyms:1-((2R,4S,5S)-4-Amino-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-benzyloxymethyl-1H-pyrimidine-2,4-dione;

Suppliers and Price of Thymidine, 3'-amino-3'-deoxy-a-(phenylmethoxy)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Thymidine, 3'-amino-3'-deoxy-a-(phenylmethoxy)-

Chemical Property:

PSA：119.57000
Density:1.325±0.06 g/cm3(Predicted)
LogP:0.56080

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Thymidine, 3'-amino-3'-deoxy-a-(phenylmethoxy)-

There total 3 articles about Thymidine, 3'-amino-3'-deoxy-a-(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 139703-08-5
1-(5'-O-acetyl-3'-phthalimido-2',3'-dideoxy-β-D-erythropentafuranosyl)-5-benzyloxymethyluracil

: 137022-35-6
3'-amino-2',3'-dideoxy-5-benzyloxymethyluridine

Guidance literature:: With MaNH₂; In ethanol; at 90 ℃;
DOI:10.3891/acta.chem.scand.46-0077

Reference yield:

: 123212-51-1
1,5-Di-O-acetyl-2,3-dideoxy-3-phthalimido-β-D-erythro-pentofuranose

: 137022-35-6
3'-amino-2',3'-dideoxy-5-benzyloxymethyluridine

Guidance literature:: Multi-step reaction with 2 steps

1: 28 percent / trimethylsilyl triflate / acetonitrile / -30 °C

2: 94 percent / MaNH₂ / ethanol / 90 °C

With trimethylsilyl trifluoromethanesulfonate; In ethanol; acetonitrile;
DOI:10.3891/acta.chem.scand.46-0077

Reference yield:

: 98808-20-9
O,O'-bis(trimethylsilyl)-5-benzyloxymethyluracil

: 137022-35-6
3'-amino-2',3'-dideoxy-5-benzyloxymethyluridine

Guidance literature:: Multi-step reaction with 2 steps

1: 28 percent / trimethylsilyl triflate / acetonitrile / -30 °C

2: 94 percent / MaNH₂ / ethanol / 90 °C

With trimethylsilyl trifluoromethanesulfonate; In ethanol; acetonitrile;
DOI:10.3891/acta.chem.scand.46-0077