2-hydroxybenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone

Base Information

• Chemical Name: 2-hydroxybenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone
• CAS No.: 304871-56-5
• Molecular Formula: C₁₆H₁₂N₆O
• Molecular Weight: 304.311
• Mol file: 304871-56-5.mol

Synonyms:

Chemical Property of 2-hydroxybenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone

Chemical Property:

• Boiling Point: 606.9±61.0 °C(Predicted)
• PKA: 7.72±0.70(Predicted)
• Density: 1.50±0.1 g/cm3(Predicted)

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-hydroxybenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone

There total 1 articles about 2-hydroxybenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-hydrazino-5H-[1,2,4]triazino[5,6-b]indole (31523-22-5) + salicylaldehyde (90-02-8) → C16H12N6O (304871-56-5)

Guidance literature:

With acetic acid; In ethanol; at 80 ℃; for 5h;

DOI:10.1007/s00044-012-0342-1

Reference yield: 56.0%

C16H12N6O (304871-56-5) → 1-(2-hydroxy)phenyl-10H-[1,2,4]triazolo[3',4':3,4][1,2,4]triazino[5,6-b]indole (1416370-27-8)

Guidance literature:

With thionyl chloride; at 75 ℃; for 4h; regiospecific reaction; Inert atmosphere;

DOI:10.1007/s00044-012-0342-1

upstream raw materials:

3-hydrazino-5H-[1,2,4]triazino[5,6-b]indole

salicylaldehyde

Downstream raw materials:

1-(2-hydroxy)phenyl-10H-[1,2,4]triazolo[3',4':3,4][1,2,4]triazino[5,6-b]indole