Ala-Ala-Gly

Base Information

• Chemical Name: Ala-Ala-Gly
• CAS No.: 25198-71-4
• Molecular Formula: C₈H₁₅N₃O₄
• Molecular Weight: 217.225
• Mol file: 25198-71-4.mol

Synonyms:

Chemical Property of Ala-Ala-Gly

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ala-Ala-Gly

There total 6 articles about Ala-Ala-Gly which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyldioctylamine (4455-26-9) → Ala-Ala-Gly (25198-71-4,55386-82-8,80064-68-2,16422-07-4)

Guidance literature:

With L-alanine N-carboxyanhydride; at -65 ℃; und anschliessend mit wss.Ba(OH)2;

DOI:10.1039/jr9500003461

Reference yield:

methyl 2-((2S)-2-((tert-butoxycarbonyl)amino)propanamido)acetate (26061-06-3,67706-13-2,28369-58-6) → Ala-Ala-Gly (25198-71-4,55386-82-8,80064-68-2,16422-07-4)

Guidance literature:

Multi-step reaction with 4 steps

1: HCl / diethyl ether

2: DCC, Et₃N / CH₂Cl₂

3: aq. NaOH / dioxane

4: CF₃CO₂H

With hydrogenchloride; sodium hydroxide; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; In 1,4-dioxane; diethyl ether; dichloromethane;

Reference yield:

L-alanylglycine methyl ester (51513-59-8) → Ala-Ala-Gly (25198-71-4,55386-82-8,80064-68-2,16422-07-4)

Guidance literature:

Multi-step reaction with 3 steps

1: DCC, Et₃N / CH₂Cl₂

2: aq. NaOH / dioxane

3: CF₃CO₂H

With sodium hydroxide; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; In 1,4-dioxane; dichloromethane;

upstream raw materials:

Boc-Ala-Ala-Gly-OH

methyldioctylamine

methyl 2-((2S)-2-((tert-butoxycarbonyl)amino)propanamido)acetate

L-alanylglycine methyl ester