C₂₈H₂₂N₂O

Base Information

• Chemical Name: C₂₈H₂₂N₂O
• CAS No.: 1300749-15-8
• Molecular Formula: C₂₈H₂₂N₂O
• Molecular Weight: 402.495
• Mol file: 1300749-15-8.mol

Synonyms:

Chemical Property of C₂₈H₂₂N₂O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₂₂N₂O

There total 3 articles about C₂₈H₂₂N₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

(E)-3-(1-triphenylmethylimidazol-4-yl)-2-propenyl 2-propynyl ether (1300748-83-7) → C28H22N2O (1300749-15-8) + C28H24N2O (1300748-85-9)

Guidance literature:

In benzene; at 145 ℃; for 26h; Inert atmosphere;

DOI:10.1039/c0ob00657b

Reference yield:

C26H22N2O2 (112606-55-0) → C28H22N2O (1300749-15-8) + C28H24N2O (1300748-85-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: diisobutylaluminium hydride

2.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / Inert atmosphere; Cooling with ice

2.2: 20 °C / Inert atmosphere; Cooling with ice

2.3: 20 °C / Inert atmosphere

3.1: benzene / 26 h / 145 °C / Inert atmosphere

With sodium hydride; diisobutylaluminium hydride; In tetrahydrofuran; mineral oil; benzene;

DOI:10.1039/c0ob00657b

Reference yield:

1-(1-Trityl-1H-imidazol4-yl)propen-3-ol (199007-50-6) → C28H22N2O (1300749-15-8) + C28H24N2O (1300748-85-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / Inert atmosphere; Cooling with ice

1.2: 20 °C / Inert atmosphere; Cooling with ice

1.3: 20 °C / Inert atmosphere

2.1: benzene / 26 h / 145 °C / Inert atmosphere

With sodium hydride; In tetrahydrofuran; mineral oil; benzene;

DOI:10.1039/c0ob00657b

upstream raw materials:

C₂₆H₂₂N₂O₂

(E)-3-(1-triphenylmethylimidazol-4-yl)-2-propenyl 2-propynyl ether

1-(1-Trityl-1H-imidazol4-yl)propen-3-ol

Refernces