2-imino-3-(2'-amino-4'-chlorophenyl)-5-methylthiazolidine dihydrochloride

Base Information

• Chemical Name: 2-imino-3-(2'-amino-4'-chlorophenyl)-5-methylthiazolidine dihydrochloride
• CAS No.: 100417-23-0
• Molecular Formula: C₁₀H₁₂ClN₃S*2ClH
• Molecular Weight: 314.666
• Mol file: 100417-23-0.mol

Synonyms:

Chemical Property of 2-imino-3-(2'-amino-4'-chlorophenyl)-5-methylthiazolidine dihydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-imino-3-(2'-amino-4'-chlorophenyl)-5-methylthiazolidine dihydrochloride

There total 6 articles about 2-imino-3-(2'-amino-4'-chlorophenyl)-5-methylthiazolidine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+/-)-2-(4-Chloro-2-nitranilino)-1-methylethanol (100418-30-2) → 2-imino-3-(2'-amino-4'-chlorophenyl)-5-methylthiazolidine dihydrochloride (100417-23-0,130131-28-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 65 percent / pyridine / Ambient temperature

2: 72 percent / Heating

3: H₂ / 10percent Pd-C / Ambient temperature; normal pressure

4: HCl gas

With pyridine; hydrogenchloride; hydrogen; palladium on activated charcoal;

DOI:10.1016/S0040-4020(01)89768-4

Reference yield:

4-chloro-2-nitro-N-(2-methyl-2-thiocyanatoethyl)-aniline (100418-43-7) → 2-imino-3-(2'-amino-4'-chlorophenyl)-5-methylthiazolidine dihydrochloride (100417-23-0,130131-28-1)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / 10percent Pd-C / Ambient temperature; normal pressure

2: HCl gas

With hydrogenchloride; hydrogen; palladium on activated charcoal;

DOI:10.1016/S0040-4020(01)89768-4

Reference yield:

4-chloro-N-(2-methyl-2-mesyloxyethyl)-2-nitroaniline (130131-38-3) → 2-imino-3-(2'-amino-4'-chlorophenyl)-5-methylthiazolidine dihydrochloride (100417-23-0,130131-28-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 72 percent / Heating

2: H₂ / 10percent Pd-C / Ambient temperature; normal pressure

3: HCl gas

With hydrogenchloride; hydrogen; palladium on activated charcoal;

DOI:10.1016/S0040-4020(01)89768-4

upstream raw materials:

(+/-)-2-(4-Chloro-2-nitranilino)-1-methylethanol

4-chloro-2-nitro-N-(2-methyl-2-thiocyanatoethyl)-aniline

4-chloro-N-(2-methyl-2-mesyloxyethyl)-2-nitroaniline

2,5-dichloronitrobenzene

Refernces

• 1、 -. "Iminothiazolidine derivatives". . . Retrieved 2008/06/13.