2-(2,5-dimethoxy-4-methylphenyl)-N-(2-methoxybenzyl)ethanamine

Base Information

• Chemical Name: 2-(2,5-dimethoxy-4-methylphenyl)-N-(2-methoxybenzyl)ethanamine
• CAS No.: 1354632-02-2
• Molecular Formula: C₁₉H₂₅NO₃
• Molecular Weight: 315.412

Synonyms:

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Chemical Property of 2-(2,5-dimethoxy-4-methylphenyl)-N-(2-methoxybenzyl)ethanamine

Chemical Property:

• Boiling Point: 439.8±40.0 °C(Predicted)
• Density: 1.063±0.06 g/cm3(Predicted)

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2,5-dimethoxy-4-methylphenyl)-N-(2-methoxybenzyl)ethanamine

There total 2 articles about 2-(2,5-dimethoxy-4-methylphenyl)-N-(2-methoxybenzyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C19H23NO3 → 2-(2,5-dimethoxy-4-methylphenyl)-N-(2-methoxybenzyl)ethanamine (1354632-02-2)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 0.5h;

DOI:10.1021/cn400216u

Reference yield:

ortho-anisaldehyde (135-02-4) + 2,5-dimethoxy-4-methyl-β-phenethylamine hydrochloride (25505-65-1) → 2-(2,5-dimethoxy-4-methylphenyl)-N-(2-methoxybenzyl)ethanamine (1354632-02-2)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / ethanol / 20 °C

2: sodium tetrahydroborate / ethanol / 0.5 h / 20 °C

With sodium tetrahydroborate; triethylamine; In ethanol;

DOI:10.1021/cn400216u

upstream raw materials:

ortho-anisaldehyde

2,5-dimethoxy-4-methyl-β-phenethylamine hydrochloride