C₂₅H₃₀O₃

Base Information

• Chemical Name: C₂₅H₃₀O₃
• CAS No.: 1151549-93-7
• Molecular Formula: C₂₅H₃₀O₃
• Molecular Weight: 378.511
• Mol file: 1151549-93-7.mol

Synonyms:

Chemical Property of C₂₅H₃₀O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₃₀O₃

There total 7 articles about C₂₅H₃₀O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C29H38O5 → C25H30O3 (1151549-93-7)

Guidance literature:

With camphor-10-sulfonic acid; In methanol; at 20 ℃; for 10h;

DOI:10.1016/j.bmcl.2012.04.062

Reference yield:

1-carbomethoxy-3,5-dihydroxybenzene (2150-44-9) → C25H30O3 (1151549-93-7)

Guidance literature:

Multi-step reaction with 10 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 12 h / 20 °C

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 20 °C

3.1: 1H-imidazole; dmap / 5 h / 20 °C

4.1: n-butyllithium / tetrahydrofuran / 0.5 h / 0 °C

4.2: 6 h / 20 °C

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C

6.1: pyridinium chlorochromate / dichloromethane / 3 h / 20 °C / Molecular sieve

7.1: triphenylphosphine; zinc / dichloromethane / 1.5 h / 20 °C

8.1: triethylamine; phosphonic acid diethyl ester / N,N-dimethyl-formamide / 2 h / 20 °C

9.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / ethanol / 6 h / 60 °C

10.1: camphor-10-sulfonic acid / methanol / 10 h / 20 °C

With 1H-imidazole; dmap; lithium aluminium tetrahydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; sodium hydride; potassium carbonate; triethylamine; phosphonic acid diethyl ester; triphenylphosphine; pyridinium chlorochromate; zinc; In tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; 7.1: Ramirez olefination reaction / 9.1: Suzuki-Miyaura cross-coupling reaction;

DOI:10.1016/j.bmcl.2012.04.062

Reference yield:

tert-butyl[(4-(2E-3,7-dimethyl-2,6-octadienyl)-3,5-bis(methoxymethoxy)benzyl)oxy]dimethylsilane (252679-36-0) → C25H30O3 (1151549-93-7)

Guidance literature:

Multi-step reaction with 6 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C

2: pyridinium chlorochromate / dichloromethane / 3 h / 20 °C / Molecular sieve

3: triphenylphosphine; zinc / dichloromethane / 1.5 h / 20 °C

4: triethylamine; phosphonic acid diethyl ester / N,N-dimethyl-formamide / 2 h / 20 °C

5: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / ethanol / 6 h / 60 °C

6: camphor-10-sulfonic acid / methanol / 10 h / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; potassium carbonate; triethylamine; phosphonic acid diethyl ester; triphenylphosphine; pyridinium chlorochromate; zinc; In tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; 3: Ramirez olefination reaction / 5: Suzuki-Miyaura cross-coupling reaction;

DOI:10.1016/j.bmcl.2012.04.062

upstream raw materials:

C₂₂H₃₀Br₂O₄

C₂₂H₃₁BrO₄

1-carbomethoxy-3,5-dihydroxybenzene

[3,5-bis(methoxymethoxy)phenyl]methanol