3-(4-Hydroxy-3-methoxyphenyl)propanenitrile

Base Information

Chemical Name:3-(4-Hydroxy-3-methoxyphenyl)propanenitrile
CAS No.:1057676-75-1
Molecular Formula:C₁₀H₁₁NO₂
Molecular Weight:177.203
Hs Code.:
DSSTox Substance ID:DTXSID001275890

Synonyms:3-(4-HYDROXY-3-METHOXYPHENYL)PROPANENITRILE;1057676-75-1;DTXSID001275890;AKOS006306879;4-Hydroxy-3-methoxybenzenepropanenitrile;EN300-1855981

Suppliers and Price of 3-(4-Hydroxy-3-methoxyphenyl)propanenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(4-Hydroxy-3-methoxyphenyl)propanenitrile

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:177.078978594
Heavy Atom Count:13
Complexity:196

Purity/Quality:

Safty Information:

Pictogram(s):
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MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)CCC#N)O

Technology Process of 3-(4-Hydroxy-3-methoxyphenyl)propanenitrile

There total 2 articles about 3-(4-Hydroxy-3-methoxyphenyl)propanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(4-hydroxy-3-methoxybenzyl)malononitrile

: 1057676-75-1
3-(4-hydroxy-3-methoxyphenyl)propanenitrile

Guidance literature:: 2-(4-hydroxy-3-methoxybenzyl)malononitrile; With bis(cyclopentadienyl)titanium dichloride; chloro-trimethyl-silane; 2,4,6-collidine hydrochloride; zinc(II) chloride; zinc; In tetrahydrofuran; at 35 ℃; for 24h; Schlenk technique; Inert atmosphere; Sealed tube;

With tetrabutyl ammonium fluoride; water; In tetrahydrofuran; for 0.5h; Schlenk technique; Inert atmosphere; Sealed tube;
DOI:10.1002/anie.201908372