[Pd(2-tert-butylthiomethylpyridine)(C(methyl)N(CH₂tosyl))I]

Base Information

• Chemical Name: [Pd(2-tert-butylthiomethylpyridine)(C(methyl)N(CH₂tosyl))I]
• CAS No.: 958877-48-0
• Molecular Formula: C₂₀H₂₇IN₂O₂PdS₂
• Molecular Weight: 624.903
• Mol file: 958877-48-0.mol

Synonyms:

Chemical Property of [Pd(2-tert-butylthiomethylpyridine)(C(methyl)N(CH₂tosyl))I]

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of [Pd(2-tert-butylthiomethylpyridine)(C(methyl)N(CH₂tosyl))I]

There total 2 articles about [Pd(2-tert-butylthiomethylpyridine)(C(methyl)N(CH₂tosyl))I] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

[Pd(2-tert-butylthiomethylpyridine)(methyl)I] (958877-32-2) + [(p-methylphenyl)sulfonylmethyl]isonitrile (38622-91-2,36635-61-7) + 2-[(tert-butylsulfanyl)methyl]pyridine (18794-45-1) → [Pd(2-tert-butylthiomethylpyridine)(C(methyl)N(CH2tosyl))I] (958877-48-0)

Guidance literature:

In dichloromethane; addn. dropwise of tosylmethyl isocyanide (1 equiv.) in CH2Cl2 under Ar to soln. of Pd(2-tert-butylthiomethylpyridine)MeI (1 equiv.) and 2-tert-butylthiomethylpyridine in CH2Cl2; stirring for 1 h at room temp.; drying under reduced pressure; addn. of Et2O; filtration, washing with small aliquots of Et2O and with pentane; drying under vac. at room temp.;crystn., elem. anal.; Kinetics;

DOI:10.1021/om700555a

Reference yield:

[Pd(2-tert-butylthiomethylpyridine)(methyl)I] (958877-32-2) + [(p-methylphenyl)sulfonylmethyl]isonitrile (38622-91-2,36635-61-7) + iodide (14362-44-8,20461-54-5,69239-56-1) + 2-[(tert-butylsulfanyl)methyl]pyridine (18794-45-1) → [Pd(2-tert-butylthiomethylpyridine)(C(methyl)N(CH2tosyl))I] (958877-48-0)

Guidance literature:

In dichloromethane; treatment of tosylmethyl isocyanide (1 equiv.) with Pd(2-tert-butylthiomethylpyridine)MeI (1 equiv.) and 2-tert-butylthiomethylpyridine (10 equiv.) in CH2Cl2 in the presence of 10 equiv. I(1-) at room temp.; monitoring by UV; Kinetics;

DOI:10.1021/om700555a

upstream raw materials:

[Pd(2-tert-butylthiomethylpyridine)(methyl)I]

[(p-methylphenyl)sulfonylmethyl]isonitrile

iodide

2-[(tert-butylsulfanyl)methyl]pyridine