Technology Process of 6-[4-(4-methoxyphenyl)-1H-1,2,3-triazol-1-yl]hexan-1-ol
There total 3 articles about 6-[4-(4-methoxyphenyl)-1H-1,2,3-triazol-1-yl]hexan-1-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: copper(l) iodide; palladium diacetate; triethylamine; diisopropylamine; tri tert-butylphosphoniumtetrafluoroborate / 24 h / Inert atmosphere; Reflux
2: pyridine; sodium azide; potassium carbonate; copper(II) sulfate; ascorbic acid / methanol; water
With
pyridine; copper(l) iodide; sodium azide; palladium diacetate; potassium carbonate; copper(II) sulfate; triethylamine; diisopropylamine; ascorbic acid; tri tert-butylphosphoniumtetrafluoroborate;
In
methanol; water;
1: Sonogashira coupling;
DOI:10.1055/s-0030-1260256
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 4 h / 20 °C / Inert atmosphere; Darkness
2: pyridine; sodium azide; potassium carbonate; copper(II) sulfate; ascorbic acid / methanol; water
With
pyridine; 1H-imidazole; sodium azide; iodine; potassium carbonate; copper(II) sulfate; triphenylphosphine; ascorbic acid;
In
methanol; dichloromethane; water;
DOI:10.1055/s-0030-1260256
- Guidance literature:
-
With
pyridine; sodium azide; potassium carbonate; copper(II) sulfate; ascorbic acid;
In
methanol; water;
chemoselective reaction;
DOI:10.1055/s-0030-1260256