2',6'-Diethyl-3'-nitroacetanilide

Base Information

• Chemical Name: 2',6'-Diethyl-3'-nitroacetanilide
• CAS No.: 91557-77-6
• Molecular Formula: C₁₂H₁₆N₂O₃
• Molecular Weight: 236.271
• European Community (EC) Number: 653-016-0
• Mol file: 91557-77-6.mol

Synonyms:2',6'-DIETHYL-3'-NITROACETANILIDE;AKOS024323628

Chemical Property of 2',6'-Diethyl-3'-nitroacetanilide

Chemical Property:

• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 236.11609238
• Heavy Atom Count: 17
• Complexity: 288

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC1=C(C(=C(C=C1)[N+](=O)[O-])CC)NC(=O)C

Technology Process of 2',6'-Diethyl-3'-nitroacetanilide

There total 3 articles about 2',6'-Diethyl-3'-nitroacetanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-diethylaniline (579-66-8) → acetic acid-(2,6-diethyl-3-nitro-anilide) (91557-77-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent

2: 87 percent / 65percent HNO₃ / acetic acid; H₂SO₄ / 1 h / Ambient temperature

With nitric acid; In sulfuric acid; acetic acid;

Reference yield:

toluene-4-sulfonic acid-(2,6-diethyl-3-nitro-anilide) (109246-38-0) → acetic acid-(2,6-diethyl-3-nitro-anilide) (91557-77-6)

Guidance literature:

With sulfuric acid; Hydrolysis_.anschliessenden Acetylierung;

DOI:10.1139/v58-188

Reference yield:

toluene-4-sulfonic acid-(2,6-diethyl-anilide) (4703-16-6) → acetic acid-(2,6-diethyl-3-nitro-anilide) (91557-77-6)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄; acetic acid; HNO₃

2: aqueous H₂SO₄ / Hydrolysis_.anschliessenden Acetylierung

With sulfuric acid; nitric acid; acetic acid;

DOI:10.1139/v58-188

upstream raw materials:

toluene-4-sulfonic acid-(2,6-diethyl-3-nitro-anilide)

2,6-diethylaniline

toluene-4-sulfonic acid-(2,6-diethyl-anilide)

Downstream raw materials:

2,6-diethyl-3-nitroaniline