Technology Process of O-(2,4-Dichlorobenzyl)-1-benzyl-3-<(1H-imidazole-1-yl)methyl>-5-nitro-2-carboxaldehyde oxime nitrate
There total 9 articles about O-(2,4-Dichlorobenzyl)-1-benzyl-3-<(1H-imidazole-1-yl)methyl>-5-nitro-2-carboxaldehyde oxime nitrate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 82 percent
2: 1.) 50 percent NaH / 1.) 30 min, 2.) 3 h, reflux
3: 75 percent / NaBH4 / ethanol / 20 h / Ambient temperature
4: 60 percent / pyridine / 3 h / Ambient temperature
5: 1.) 50 percent NaH, / 1.) DMF, 30 min, 2.) 12 h, room temp.
6: 72 percent / SeO2 / dioxane / 3 h / Heating
7: 50 percent / NH2OH*HCl / methanol / 12 h / Ambient temperature
8: 1.) 50 percent NaH / 1.) DMF, 30 min, room temp., 2.) 12 h, room temp.
With
sodium tetrahydroborate; selenium(IV) oxide; hydroxylamine hydrochloride; sodium hydride;
In
1,4-dioxane; pyridine; methanol; ethanol;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 1.) 50 percent NaH / 1.) 30 min, 2.) 3 h, reflux
2: 75 percent / NaBH4 / ethanol / 20 h / Ambient temperature
3: 60 percent / pyridine / 3 h / Ambient temperature
4: 1.) 50 percent NaH, / 1.) DMF, 30 min, 2.) 12 h, room temp.
5: 72 percent / SeO2 / dioxane / 3 h / Heating
6: 50 percent / NH2OH*HCl / methanol / 12 h / Ambient temperature
7: 1.) 50 percent NaH / 1.) DMF, 30 min, room temp., 2.) 12 h, room temp.
With
sodium tetrahydroborate; selenium(IV) oxide; hydroxylamine hydrochloride; sodium hydride;
In
1,4-dioxane; pyridine; methanol; ethanol;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 1.) 50 percent NaH / 1.) 30 min, 2.) 3 h, reflux
2: 75 percent / NaBH4 / ethanol / 20 h / Ambient temperature
3: 60 percent / pyridine / 3 h / Ambient temperature
4: 1.) 50 percent NaH, / 1.) DMF, 30 min, 2.) 12 h, room temp.
5: 72 percent / SeO2 / dioxane / 3 h / Heating
6: 50 percent / NH2OH*HCl / methanol / 12 h / Ambient temperature
7: 1.) 50 percent NaH / 1.) DMF, 30 min, room temp., 2.) 12 h, room temp.
With
sodium tetrahydroborate; selenium(IV) oxide; hydroxylamine hydrochloride; sodium hydride;
In
1,4-dioxane; pyridine; methanol; ethanol;
