C₃₉H₄₈FN₇O₇

Base Information

Chemical Name:C₃₉H₄₈FN₇O₇
CAS No.:1332639-38-9
Molecular Formula:C₃₉H₄₈FN₇O₇
Molecular Weight:745.851
Hs Code.:

C<sub>39</sub>H<sub>48</sub>FN<sub>7</sub>O<sub>7</sub>

Synonyms:

Suppliers and Price of C₃₉H₄₈FN₇O₇

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₃₉H₄₈FN₇O₇

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₃₉H₄₈FN₇O₇

There total 29 articles about C₃₉H₄₈FN₇O₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 1332639-38-9
C₃₉H₄₈FN₇O₇

Guidance literature:: Multi-step reaction with 14 steps

1: triethylamine / dichloromethane / 2.5 h / 0 - 20 °C

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 6 h / 20 - 45 °C

3: dmap / dichloromethane / 3 h / 0 °C

4: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 °C

5: sodium periodate / ruthenium(III) trichloride hydrate / 1-methyl-pyrrolidin-2-one; tetrachloromethane; acetonitrile; water / 3.83 h

6: ethyl acetate; diethyl ether

7: lithium borohydride / tetrahydrofuran / 3 h / 0 °C

8: N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 0 °C

9: sodium azide / N,N-dimethyl-formamide / 2 h / 80 °C

10: copper(ll) sulfate pentahydrate; sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydro-furan-3-olate / ethanol; water; tert-butyl alcohol

11: trifluoroacetic acid / dichloromethane

12: HATU / 1-methyl-pyrrolidin-2-one

13: trifluoroacetic acid / dichloromethane

14: HATU / 1-methyl-pyrrolidin-2-one

With dmap; sodium periodate; lithium borohydride; sodium azide; copper(ll) sulfate pentahydrate; sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydro-furan-3-olate; tetrabutyl ammonium fluoride; sodium hydride; triethylamine; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; ruthenium(III) trichloride hydrate; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; tetrachloromethane; diethyl ether; ethanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;

Reference yield:

: 187039-57-2,335280-19-8
(2S,3S)-1-(tert-butoxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic acid

: 1332639-38-9
C₃₉H₄₈FN₇O₇

Guidance literature:: Multi-step reaction with 22 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 0 - 90 °C

2.1: 1H-imidazole / dichloromethane / 6 h / 0 - 20 °C

3.1: lithium borohydride / tetrahydrofuran / 3 h / 0 - 20 °C

4.1: triethylamine; sulfur trioxide pyridine complex / dichloromethane; dimethyl sulfoxide / 2 h / 0 - 20 °C

5.1: triethylamine / 12 h

6.1: thionyl chloride / dichloromethane / 1 h / -78 °C

6.2: 1 h / -78 °C

7.1: / acetonitrile / 16 h / 20 °C

8.1: hydrogen / ethanol / 1.5 h / 2585.81 Torr

9.1: triethylamine / dichloromethane / 2.5 h / 0 - 20 °C

10.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 6 h / 20 - 45 °C

11.1: dmap / dichloromethane / 3 h / 0 °C

12.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 °C

13.1: sodium periodate / ruthenium(III) trichloride hydrate / 1-methyl-pyrrolidin-2-one; tetrachloromethane; acetonitrile; water / 3.83 h

14.1: ethyl acetate; diethyl ether

15.1: lithium borohydride / tetrahydrofuran / 3 h / 0 °C

16.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 0 °C

17.1: sodium azide / N,N-dimethyl-formamide / 2 h / 80 °C

18.1: copper(ll) sulfate pentahydrate; sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydro-furan-3-olate / ethanol; water; tert-butyl alcohol

19.1: trifluoroacetic acid / dichloromethane

20.1: HATU / 1-methyl-pyrrolidin-2-one

21.1: trifluoroacetic acid / dichloromethane

22.1: HATU / 1-methyl-pyrrolidin-2-one

With 1H-imidazole; dmap; sodium periodate; lithium borohydride; thionyl chloride; sodium azide; copper(ll) sulfate pentahydrate; sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydro-furan-3-olate; tetrabutyl ammonium fluoride; hydrogen; sulfur trioxide pyridine complex; sodium hydride; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; ruthenium(III) trichloride hydrate; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; tetrachloromethane; diethyl ether; ethanol; dichloromethane; water; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;

Reference yield:

: 184046-78-4
(2S,3S)-1-tert-butyl-2-methyl 3-hydroxypyrrolidine-1,2-dicarboxylate

: 1332639-38-9
C₃₉H₄₈FN₇O₇

Guidance literature:: Multi-step reaction with 21 steps

1.1: 1H-imidazole / dichloromethane / 6 h / 0 - 20 °C

2.1: lithium borohydride / tetrahydrofuran / 3 h / 0 - 20 °C

3.1: triethylamine; sulfur trioxide pyridine complex / dichloromethane; dimethyl sulfoxide / 2 h / 0 - 20 °C

4.1: triethylamine / 12 h

5.1: thionyl chloride / dichloromethane / 1 h / -78 °C

5.2: 1 h / -78 °C

6.1: / acetonitrile / 16 h / 20 °C

7.1: hydrogen / ethanol / 1.5 h / 2585.81 Torr

8.1: triethylamine / dichloromethane / 2.5 h / 0 - 20 °C

9.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 6 h / 20 - 45 °C

10.1: dmap / dichloromethane / 3 h / 0 °C

11.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 °C

12.1: sodium periodate / ruthenium(III) trichloride hydrate / 1-methyl-pyrrolidin-2-one; tetrachloromethane; acetonitrile; water / 3.83 h

13.1: ethyl acetate; diethyl ether

14.1: lithium borohydride / tetrahydrofuran / 3 h / 0 °C

15.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 0 °C

16.1: sodium azide / N,N-dimethyl-formamide / 2 h / 80 °C

17.1: copper(ll) sulfate pentahydrate; sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydro-furan-3-olate / ethanol; water; tert-butyl alcohol

18.1: trifluoroacetic acid / dichloromethane

19.1: HATU / 1-methyl-pyrrolidin-2-one

20.1: trifluoroacetic acid / dichloromethane

21.1: HATU / 1-methyl-pyrrolidin-2-one

With 1H-imidazole; dmap; sodium periodate; lithium borohydride; thionyl chloride; sodium azide; copper(ll) sulfate pentahydrate; sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydro-furan-3-olate; tetrabutyl ammonium fluoride; hydrogen; sulfur trioxide pyridine complex; sodium hydride; triethylamine; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; ruthenium(III) trichloride hydrate; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; tetrachloromethane; diethyl ether; ethanol; dichloromethane; water; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;