2-[(4-methylbenzoyl)amino]-4-pentenoic acid

Base Information

• Chemical Name: 2-[(4-methylbenzoyl)amino]-4-pentenoic acid
• CAS No.: 944070-57-9
• Molecular Formula: C₁₃H₁₅NO₃
• Molecular Weight: 233.267
• Mol file: 944070-57-9.mol

Synonyms:

Chemical Property of 2-[(4-methylbenzoyl)amino]-4-pentenoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-[(4-methylbenzoyl)amino]-4-pentenoic acid

There total 1 articles about 2-[(4-methylbenzoyl)amino]-4-pentenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H15N2O2Pol → 2-[(4-methylbenzoyl)amino]-4-pentenoic acid (944070-57-9) + N-[(1-aminocarbonyl)-1-buten-4-yl]-4-methylbenzamide (1586780-38-2)

Guidance literature:

With water; trifluoroacetic acid; at 20 ℃; for 2h; Rink amide MBHA resin

DOI:10.1021/jo500273f

Reference yield:

2-[(4-methylbenzoyl)amino]-4-pentenoic acid (944070-57-9) → C13H13NO2 (1349803-46-8)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1039/c1ob06629c

Reference yield:

2-[(4-methylbenzoyl)amino]-4-pentenoic acid (944070-57-9) → C15H19NO3 (1356843-94-1)

Guidance literature:

Multi-step reaction with 2 steps

1: dicyclohexyl-carbodiimide / dichloromethane / 2 h / 20 °C

2: C₃₉H₄₈N₆S / dichloromethane / 36 h / -20 °C

With C₃₉H₄₈N₆S; dicyclohexyl-carbodiimide; In dichloromethane;

DOI:10.1039/c1ob06629c

Downstream raw materials:

C₁₃H₁₃NO₂

C₁₅H₁₉NO₃