phthalic acid 1-allyl ester 2-[((2R,5R)-5-ethyl-1-aza-bicyclo[2.2.2]oct-2-yl)(6-methoxyquinolin-4-yl)-(S)-methyl] ester

Base Information

• Chemical Name: phthalic acid 1-allyl ester 2-[((2R,5R)-5-ethyl-1-aza-bicyclo[2.2.2]oct-2-yl)(6-methoxyquinolin-4-yl)-(S)-methyl] ester
• CAS No.: 769196-71-6
• Molecular Formula: C₃₁H₃₄N₂O₅
• Molecular Weight: 514.621
• Mol file: 769196-71-6.mol

Synonyms:

Chemical Property of phthalic acid 1-allyl ester 2-[((2R,5R)-5-ethyl-1-aza-bicyclo[2.2.2]oct-2-yl)(6-methoxyquinolin-4-yl)-(S)-methyl] ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phthalic acid 1-allyl ester 2-[((2R,5R)-5-ethyl-1-aza-bicyclo[2.2.2]oct-2-yl)(6-methoxyquinolin-4-yl)-(S)-methyl] ester

There total 2 articles about phthalic acid 1-allyl ester 2-[((2R,5R)-5-ethyl-1-aza-bicyclo[2.2.2]oct-2-yl)(6-methoxyquinolin-4-yl)-(S)-methyl] ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Phthaloyl dichloride (88-95-9) → phthalic acid 1-allyl ester 2-[((2R,5R)-5-ethyl-1-aza-bicyclo[2.2.2]oct-2-yl)(6-methoxyquinolin-4-yl)-(S)-methyl] ester (769196-71-6)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 20 °C

2: 3.0 g / CH₂Cl₂

With triethylamine; In dichloromethane;

DOI:10.1039/b406341d

Reference yield:

2-chlorocarbonyl-benzoic acid allyl ester + dihydroquinidine hydrochloride → phthalic acid 1-allyl ester 2-[((2R,5R)-5-ethyl-1-aza-bicyclo[2.2.2]oct-2-yl)(6-methoxyquinolin-4-yl)-(S)-methyl] ester (769196-71-6)

Guidance literature:

In dichloromethane;

DOI:10.1039/b406341d

upstream raw materials:

Phthaloyl dichloride