Technology Process of trans-3-(N-ethyl-N-hydroxyethylamino)-8-benzyloxy-5-methoxy-1,2,3,4-tetrahydro-2-naphthol
There total 8 articles about trans-3-(N-ethyl-N-hydroxyethylamino)-8-benzyloxy-5-methoxy-1,2,3,4-tetrahydro-2-naphthol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 3h;
Heating;
DOI:10.1135/cccc19921111
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 90 percent / pyridine / benzene / 3 h / Heating
2: 60 percent / 6 percent monoperphthalic acid in ether / 168 h / Ambient temperature
3: 180 mg / NaOH / H2O / 3 h / Heating
4: pyridine / CHCl3 / 48 h / Ambient temperature
5: 1.) KOH, 2.) conc. HCl / 1.) water, 0 deg C, 1 h, 2.) water, 0 deg C, 30 min
6: 62 percent / sodium, ethanol / 1 h / Heating
7: 68 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating
With
pyridine; hydrogenchloride; potassium hydroxide; sodium hydroxide; lithium aluminium tetrahydride; monoperoxyphthalic acid; ethanol; sodium;
In
tetrahydrofuran; chloroform; water; benzene;
DOI:10.1135/cccc19921111
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 55 percent / NaOH / H2O / 1.5 h / 30 °C
2: 90 percent / pyridine / benzene / 3 h / Heating
3: 60 percent / 6 percent monoperphthalic acid in ether / 168 h / Ambient temperature
4: 180 mg / NaOH / H2O / 3 h / Heating
5: pyridine / CHCl3 / 48 h / Ambient temperature
6: 1.) KOH, 2.) conc. HCl / 1.) water, 0 deg C, 1 h, 2.) water, 0 deg C, 30 min
7: 62 percent / sodium, ethanol / 1 h / Heating
8: 68 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating
With
pyridine; hydrogenchloride; potassium hydroxide; sodium hydroxide; lithium aluminium tetrahydride; monoperoxyphthalic acid; ethanol; sodium;
In
tetrahydrofuran; chloroform; water; benzene;
DOI:10.1135/cccc19921111
