C₂₉H₃₄N₂O₄

Base Information

• Chemical Name: C₂₉H₃₄N₂O₄
• CAS No.: 1610524-31-6
• Molecular Formula: C₂₉H₃₄N₂O₄
• Molecular Weight: 474.6
• Mol file: 1610524-31-6.mol

Synonyms:

Chemical Property of C₂₉H₃₄N₂O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₃₄N₂O₄

There total 8 articles about C₂₉H₃₄N₂O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C47H52N2O6 (1610524-05-4) → C29H34N2O4 (1610524-31-6)

Guidance literature:

With acetic acid; In water; at 80 ℃; for 5h;

DOI:10.1016/j.bmcl.2014.04.069

Reference yield:

5-bromo-2-hydroxybenzyl alcohol (2316-64-5) → C29H34N2O4 (1610524-31-6)

Guidance literature:

Multi-step reaction with 8 steps

1: acetone

2: n-butyllithium / tetrahydrofuran

3: sodium hexamethyldisilazane / tetrahydrofuran

4: bromine

5: triethylamine / dichloromethane

6: sodium tetrahydroborate / tetrahydrofuran; methanol

7: 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium t-butanolate / toluene / 5 h / 80 °C

8: acetic acid / water / 5 h / 80 °C

With sodium tetrahydroborate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; n-butyllithium; bromine; sodium hexamethyldisilazane; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; acetic acid; triethylamine; sodium t-butanolate; In tetrahydrofuran; methanol; dichloromethane; water; acetone; toluene; 7: |Buchwald-Hartwig Coupling;

DOI:10.1016/j.bmcl.2014.04.069

Reference yield:

6-bromo-2,2-dimethyl-4H-benzo[1,3]dioxine (52113-69-6) → C29H34N2O4 (1610524-31-6)

Guidance literature:

Multi-step reaction with 7 steps

1: n-butyllithium / tetrahydrofuran

2: sodium hexamethyldisilazane / tetrahydrofuran

3: bromine

4: triethylamine / dichloromethane

5: sodium tetrahydroborate / tetrahydrofuran; methanol

6: 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium t-butanolate / toluene / 5 h / 80 °C

7: acetic acid / water / 5 h / 80 °C

With sodium tetrahydroborate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; n-butyllithium; bromine; sodium hexamethyldisilazane; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; acetic acid; triethylamine; sodium t-butanolate; In tetrahydrofuran; methanol; dichloromethane; water; toluene; 6: |Buchwald-Hartwig Coupling;

DOI:10.1016/j.bmcl.2014.04.069

upstream raw materials:

5-bromo-2-hydroxybenzyl alcohol

6-bromo-2,2-dimethyl-4H-benzo[1,3]dioxine

1-(2,2-dimethyl-4H-benzo[d][1,3]dioxan-6-yl)ethanone

2-bromo-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)ethanone

Refernces