9-<2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentofuranosyl>-N⁶-<(dimethylamino)methylidene>adenine 3'-(triethylammonium phosphonate)

Base Information

• Chemical Name: 9-<2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentofuranosyl>-N⁶-<(dimethylamino)methylidene>adenine 3'-(triethylammonium phosphonate)
• CAS No.: 139260-84-7
• Molecular Formula: C₆H₁₅N*C₃₄H₃₇N₆O₇P
• Molecular Weight: 773.869

Synonyms:

Chemical Property of 9-<2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentofuranosyl>-N⁶-<(dimethylamino)methylidene>adenine 3'-(triethylammonium phosphonate)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9-<2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentofuranosyl>-N⁶-<(dimethylamino)methylidene>adenine 3'-(triethylammonium phosphonate)

There total 3 articles about 9-<2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentofuranosyl>-N⁶-<(dimethylamino)methylidene>adenine 3'-(triethylammonium phosphonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-(2'-deoxy-β-D-threo-ribofuranosyl)-adenine (13276-53-4,7005-15-4) → 9-<2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentofuranosyl>-N6-<(dimethylamino)methylidene>adenine 3'-(triethylammonium phosphonate) (139260-84-7)

Guidance literature:

Multi-step reaction with 3 steps

1: dimethylformamide / 18 h

2: pyridine, (i-Pr)2EtN / 3.5 h / Ambient temperature

3: 1.) PCl₃, N-methylmorpholine, 1,2,4-triazole / 1.) CH₂Cl₂, 10 min, r.t.

With 4-methyl-morpholine; pyridine; 1,2,4-Triazole; N-ethyl-N,N-diisopropylamine; phosphorus trichloride; In N,N-dimethyl-formamide;

DOI:10.1002/hlca.19910740840

Reference yield:

4,4'-dimethoxytrityl chloride (40615-36-9) → 9-<2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentofuranosyl>-N6-<(dimethylamino)methylidene>adenine 3'-(triethylammonium phosphonate) (139260-84-7)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine, (i-Pr)2EtN / 3.5 h / Ambient temperature

2: 1.) PCl₃, N-methylmorpholine, 1,2,4-triazole / 1.) CH₂Cl₂, 10 min, r.t.

With 4-methyl-morpholine; pyridine; 1,2,4-Triazole; N-ethyl-N,N-diisopropylamine; phosphorus trichloride;

DOI:10.1002/hlca.19910740840

Reference yield:

triethylamine carbonate (15715-58-9) + 9-<2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentofuranosyl>-N6-<(dimethylamino)methylidene>adenine (139260-82-5,869355-14-6) → 9-<2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentofuranosyl>-N6-<(dimethylamino)methylidene>adenine 3'-(triethylammonium phosphonate) (139260-84-7)

Guidance literature:

With 4-methyl-morpholine; 1,2,4-Triazole; phosphorus trichloride; Yield given. Multistep reaction; 1.) CH₂Cl₂, 10 min, r.t.;

DOI:10.1002/hlca.19910740840

upstream raw materials:

triethylamine carbonate

9-<2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentofuranosyl>-N⁶-<(dimethylamino)methylidene>adenine

4,4'-dimethoxytrityl chloride

9-(2'-deoxy-β-D-threo-ribofuranosyl)-adenine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 139260-84-7 9-<2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentofuranosyl>-N⁶-<(dimethylamino)methylidene>adenine 3'-(triethylammonium phosphonate)

Send

Send

Metric Ton KG G Pound L ML

Send

Send