Dextromethorphan N-Oxide

Base Information Edit

Chemical Name:Dextromethorphan N-Oxide
CAS No.:1177494-18-6
Molecular Formula:C₁₈H₂₅NO₂
Molecular Weight:287.402
Hs Code.:
UNII:BC3V89U68A
Mol file:1177494-18-6.mol

Synonyms:Dextromethorphan N-Oxide;(+)-Dextromethorphan N-Oxide;BC3V89U68A;UNII-BC3V89U68A;(17RS)-ent-3-Methoxy-17-methylmorphinan 17-oxide;1177494-18-6

Suppliers and Price of Dextromethorphan N-Oxide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Dextromethorphan N-Oxide Edit

Chemical Property:

PKA:5.13±0.20(Predicted)
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:287.188529040
Heavy Atom Count:21
Complexity:414

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C[N+]1(CCC23CCCCC2C1CC4=C3C=C(C=C4)OC)[O-]
Isomeric SMILES:C[N+]1(CC[C@@]23CCCC[C@@H]2[C@@H]1CC4=C3C=C(C=C4)OC)[O-]
Uses DextroMethorphan N-Oxide can be used in the process for preparation of (+)-Morphinan N-oxides.

Technology Process of Dextromethorphan N-Oxide

There total 3 articles about Dextromethorphan N-Oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 125-71-3,1453167-99-1
dextromethorphan

: 113951-05-6,1177494-18-6
dextromethorphan N-oxide

Guidance literature:: With perfluoro-cis-2-n-butyl-3-n-propyloxaziridine; HCFC-225ca,cb; In dichloromethane; at -60 ℃; for 0.333333h;
DOI:10.1016/S0040-4020(98)00417-7

Reference yield: 87.0%

: 6700-34-1
dextromethorphan hydrobromide, monohydrate

: 113951-05-6,1177494-18-6
dextromethorphan N-oxide

Guidance literature:: dextromethorphan hydrobromide, monohydrate; With sodium hydroxide; In water;

With dihydrogen peroxide; In ethanol; at 10 - 20 ℃; for 16h; Reagent/catalyst; Solvent;