C₂₉H₂₄BrClN₂O₂

Base Information

• Chemical Name: C₂₉H₂₄BrClN₂O₂
• CAS No.: 936566-18-6
• Molecular Formula: C₂₉H₂₄BrClN₂O₂
• Molecular Weight: 547.879
• Mol file: 936566-18-6.mol

Synonyms:

Chemical Property of C₂₉H₂₄BrClN₂O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₂₄BrClN₂O₂

There total 5 articles about C₂₉H₂₄BrClN₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

1,4-dibromo-butane (110-52-1) + C25H17ClN2O2 (936566-17-5) → C29H24BrClN2O2 (936566-18-6)

Guidance literature:

C₂₅H₁₇ClN₂O₂; With potassium carbonate; In acetone; for 0.5h; Heating;

1,4-dibromo-butane; In acetone; Further stages.; Heating;

DOI:10.1016/j.bmcl.2007.01.043

Reference yield:

(E)-1-(3-chlorophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one → C29H24BrClN2O2 (936566-18-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 65 percent / LiOH / tetrahydrofuran / 2 h / 25 °C

2.1: 73 percent / ammonium ferric sulphate dodecahydrate; NH₄OAC; AcOH / 3 h / Heating

3.1: BBr₃ / CH₂Cl₂ / 2 h / 25 °C

3.2: 61 percent / H₂O / CH₂Cl₂ / 1 h

4.1: K₂CO₃ / acetone / 0.5 h / Heating

4.2: 58 percent / acetone / Heating

With lithium hydroxide; ammonium iron(III) sulfate dodecahydrate; ammonium acetate; boron tribromide; potassium carbonate; acetic acid; In tetrahydrofuran; dichloromethane; acetone; 1.1: Michael addition;

DOI:10.1016/j.bmcl.2007.01.043

Reference yield:

C26H19ClN2O2 (936566-30-2) → C29H24BrClN2O2 (936566-18-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: BBr₃ / CH₂Cl₂ / 2 h / 25 °C

1.2: 61 percent / H₂O / CH₂Cl₂ / 1 h

2.1: K₂CO₃ / acetone / 0.5 h / Heating

2.2: 58 percent / acetone / Heating

With boron tribromide; potassium carbonate; In dichloromethane; acetone;

DOI:10.1016/j.bmcl.2007.01.043

upstream raw materials:

1,4-dibromo-butane

C₂₅H₁₇ClN₂O₂

C₂₆H₁₉ClN₂O₂

C₂₆H₂₂ClNO₄

Downstream raw materials:

C₃₇H₂₈ClN₃O₄