Technology Process of C25H22ClNO4
There total 4 articles about C25H22ClNO4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hydrogencarbonate; sodium hydroxide;
In
water; acetone;
at 20 ℃;
for 12h;
pH=9.5;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium tert-butylate / N,N-dimethyl-formamide / 0.33 h / 20 °C / Cooling with ice
1.2: 16 h / 25 °C / Cooling with ice
2.1: hydrogenchloride / dichloromethane; water / pH 2 - 3
3.1: 2,3-diacetoxy-(2S,3S)-butanedioic acid / methanol / 3 h / 60 - 65 °C
4.1: lithium hydroxide monohydrate; water / methanol
5.1: sodium hydroxide; sodium hydrogencarbonate / water; acetone / 12 h / 20 °C / pH 9.5
With
hydrogenchloride; lithium hydroxide monohydrate; potassium tert-butylate; water; 2,3-diacetoxy-(2S,3S)-butanedioic acid; sodium hydrogencarbonate; sodium hydroxide;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide; acetone;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: hydrogenchloride / dichloromethane; water / pH 2 - 3
2: 2,3-diacetoxy-(2S,3S)-butanedioic acid / methanol / 3 h / 60 - 65 °C
3: lithium hydroxide monohydrate; water / methanol
4: sodium hydroxide; sodium hydrogencarbonate / water; acetone / 12 h / 20 °C / pH 9.5
With
hydrogenchloride; lithium hydroxide monohydrate; water; 2,3-diacetoxy-(2S,3S)-butanedioic acid; sodium hydrogencarbonate; sodium hydroxide;
In
methanol; dichloromethane; water; acetone;
