2H-1-Benzopyran-2-one,7-isocyanato-3-phenyl

Base Information

• Chemical Name: 2H-1-Benzopyran-2-one,7-isocyanato-3-phenyl
• CAS No.: 55936-32-8
• Molecular Formula: C₁₆H₉NO₃
• Molecular Weight: 263.252
• Mol file: 55936-32-8.mol

Synonyms:

Chemical Property of 2H-1-Benzopyran-2-one,7-isocyanato-3-phenyl

Chemical Property:

• Melting Point: 233℃
• Density: 1.25

Purity/Quality:

99% ^*data from raw suppliers

7-ISOCYANATO-3-PHENYL-2H-1-BENZOPYRAN-2-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2H-1-Benzopyran-2-one,7-isocyanato-3-phenyl

There total 4 articles about 2H-1-Benzopyran-2-one,7-isocyanato-3-phenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-phenyl-7-amino-coumarin (4108-61-6) → 7-isocyanato-3-phenyl-coumarin (55936-32-8)

Guidance literature:

With chlorobenzene; Einleiten von Chlorwasserstoff und Erhitzen des entstandenen Hydrochlorids mit Phosgen;

Reference yield:

3c-(4-acetylamino-2-methoxy-phenyl)-2-phenyl-acrylonitrile (66611-71-0) → 7-isocyanato-3-phenyl-coumarin (55936-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine hydrochloride / 200 °C / anschliessend Behandeln mit Wasser

2: chlorobenzene / Einleiten von Chlorwasserstoff und Erhitzen des entstandenen Hydrochlorids mit Phosgen

With pyridine hydrochloride; chlorobenzene;

Reference yield:

phenylacetonitrile (140-29-4) → 7-isocyanato-3-phenyl-coumarin (55936-32-8)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium hydroxide; ethanol

2: pyridine hydrochloride / 200 °C / anschliessend Behandeln mit Wasser

3: chlorobenzene / Einleiten von Chlorwasserstoff und Erhitzen des entstandenen Hydrochlorids mit Phosgen

With potassium hydroxide; ethanol; pyridine hydrochloride; chlorobenzene;

upstream raw materials:

3-phenyl-7-amino-coumarin

3c-(4-acetylamino-2-methoxy-phenyl)-2-phenyl-acrylonitrile

phenylacetonitrile

2-methoxy-4-acetyl-amino-benzaldehyde

Downstream raw materials:

7-methoxycarbonylamino-3-phenyl-coumarin

3-phenyl-7-propoxycarbonylamino-coumarin

3-phenyl-7-(N'-propyl-ureido)-coumarin

7-ethoxycarbonylamino-3-phenyl-coumarin