Sulfamic acid (2S,3S)-3-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-4-oxo-azetidin-2-ylmethyl ester

Base Information

• Chemical Name: Sulfamic acid (2S,3S)-3-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-4-oxo-azetidin-2-ylmethyl ester
• CAS No.: 211515-71-8
• Molecular Formula: C₂₉H₂₈N₆O₆S₂
• Molecular Weight: 620.71
• Mol file: 211515-71-8.mol

Synonyms:

Chemical Property of Sulfamic acid (2S,3S)-3-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-4-oxo-azetidin-2-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Sulfamic acid (2S,3S)-3-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-4-oxo-azetidin-2-ylmethyl ester

There total 1 articles about Sulfamic acid (2S,3S)-3-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-4-oxo-azetidin-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Sulfamic acid (2S,3S)-3-amino-4-oxo-azetidin-2-ylmethyl ester; compound with trifluoro-acetic acid + 2-(2-aminothiazol-4-yl)-2-(methoxy)iminoacetic acid (64485-90-1) → Sulfamic acid (2S,3S)-3-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-4-oxo-azetidin-2-ylmethyl ester (211515-71-8)

Guidance literature:

With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In dichloromethane; N,N-dimethyl-formamide; Yield given; 1.) 0 deg C, 2 h, 2.) r.t., 2 h;

DOI:10.1016/S0014-827X(98)00004-4

Reference yield:

Sulfamic acid (2S,3S)-3-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-4-oxo-azetidin-2-ylmethyl ester (211515-71-8) → (3S,4S)-3-{2-[(Z)-Methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-2-oxo-4-sulfamoyloxymethyl-azetidine-1-sulfonic acid

Guidance literature:

With sulfur trioxide-N,N-dimethylformamide complex; In N,N-dimethyl-formamide; at 0 ℃; for 1.5h;

DOI:10.1016/S0014-827X(98)00004-4

upstream raw materials:

2-(2-aminothiazol-4-yl)-2-(methoxy)iminoacetic acid