17α-Aethinyl-2--19-nor-androstandiol-(3β,17β)

Base Information

• Chemical Name: 17α-Aethinyl-2--19-nor-androstandiol-(3β,17β)
• CAS No.: 105232-16-4
• Molecular Formula: C₂₈H₃₇NO₂
• Molecular Weight: 419.607
• Mol file: 105232-16-4.mol

Synonyms:

Chemical Property of 17α-Aethinyl-2--19-nor-androstandiol-(3β,17β)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 17α-Aethinyl-2--19-nor-androstandiol-(3β,17β)

There total 4 articles about 17α-Aethinyl-2--19-nor-androstandiol-(3β,17β) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

17α-Aethinyl-2--19-nor-androstanol-(17β)-on-(3) (103103-17-9) → 17α-Aethinyl-2--19-nor-androstandiol-(3β,17β) (105232-16-4)

Guidance literature:

With sodium tetrahydroborate; In 1,4-dioxane; methanol; water;

DOI:10.1021/jm00338a018

Reference yield:

[3H]-5alpha-Dihydrorethindrone (52-79-9) → 17α-Aethinyl-2--19-nor-androstandiol-(3β,17β) (105232-16-4)

Guidance literature:

Multi-step reaction with 3 steps

1: NaOMe / tetrahydrofuran; CH₂Cl₂

2: benzene; methanol / Heating

3: NaBH₄ / methanol; H₂O; dioxane

With sodium tetrahydroborate; sodium methylate; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; benzene;

DOI:10.1021/jm00338a018

Reference yield:

17α-Ethinyl-2-hydroxymethylen-19-nor-androstanol-(17β)-on-(3) (78094-41-4) → 17α-Aethinyl-2--19-nor-androstandiol-(3β,17β) (105232-16-4)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene; methanol / Heating

2: NaBH₄ / methanol; H₂O; dioxane

With sodium tetrahydroborate; In 1,4-dioxane; methanol; water; benzene;

DOI:10.1021/jm00338a018

upstream raw materials:

17α-Aethinyl-2--19-nor-androstanol-(17β)-on-(3)

[3H]-5alpha-Dihydrorethindrone

17α-Ethinyl-2-hydroxymethylen-19-nor-androstanol-(17β)-on-(3)

N-methylaniline