C₂₈H₂₁FN₂O₂

Base Information

Chemical Name:C₂₈H₂₁FN₂O₂
CAS No.:1395922-98-1
Molecular Formula:C₂₈H₂₁FN₂O₂
Molecular Weight:436.485
Hs Code.:

C<sub>28</sub>H<sub>21</sub>FN<sub>2</sub>O<sub>2</sub>

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₈H₂₁FN₂O₂

Chemical Property:

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Technology Process of C₂₈H₂₁FN₂O₂

There total 5 articles about C₂₈H₂₁FN₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 866023-58-7
N-(3-amino-4-fluorophenyl)benzamide

: 3973-54-4
2-chloro-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one

: 1395922-98-1
C₂₈H₂₁FN₂O₂

Guidance literature:: With palladium diacetate; sodium t-butanolate; XPhos; In toluene; tert-butyl alcohol; at 90 ℃; Inert atmosphere;
DOI:10.1021/jm300951u

Reference yield:

: 3973-45-3
2-(3-chlorophenethyl)benzoic acid

: 1395922-98-1
C₂₈H₂₁FN₂O₂

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1 h / 20 °C / Inert atmosphere

2: aluminum (III) chloride / dichloromethane / 4 h / 20 °C

3: palladium diacetate; XPhos; sodium t-butanolate / tert-butyl alcohol; toluene / 90 °C / Inert atmosphere

With aluminum (III) chloride; oxalyl dichloride; palladium diacetate; N,N-dimethyl-formamide; sodium t-butanolate; XPhos; In dichloromethane; toluene; tert-butyl alcohol; 2: |Friedel-Crafts Acylation / 3: |Buchwald-Hartwig Coupling;
DOI:10.1021/jm300951u

Reference yield:

: C₁₅H₁₂Cl₂O

: 1395922-98-1
C₂₈H₂₁FN₂O₂

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum (III) chloride / dichloromethane / 4 h / 20 °C

2: palladium diacetate; XPhos; sodium t-butanolate / tert-butyl alcohol; toluene / 90 °C / Inert atmosphere

With aluminum (III) chloride; palladium diacetate; sodium t-butanolate; XPhos; In dichloromethane; toluene; tert-butyl alcohol; 1: |Friedel-Crafts Acylation / 2: |Buchwald-Hartwig Coupling;
DOI:10.1021/jm300951u