Technology Process of 1-(7-hydroxyhept-5-ynyl)-2,3,4,5-tetramethoxy-6-methylbenzene
There total 5 articles about 1-(7-hydroxyhept-5-ynyl)-2,3,4,5-tetramethoxy-6-methylbenzene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
methanol;
at 70 ℃;
for 0.5h;
Yield given;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 90 percent / 70percent perchloric acid, hydrogen / 5percent palladium-charcoal / acetic acid / 1.5 h / 70 °C
2: triethylamine / CH2Cl2 / 1 h / -5 °C
3: sodium iodide / acetone / 2 h / 50 °C
4: 1.) sodium amide / 1.) Et2O, liquid ammonia, -50 deg C - -40 deg C, 60 min, 2.) -50 deg C - -40 deg C, 100 min
5: toluene-p-sulphonic acid / methanol / 0.5 h / 70 °C
With
perchloric acid; hydrogen; toluene-4-sulfonic acid; sodium amide; triethylamine; sodium iodide;
palladium on activated charcoal;
In
methanol; dichloromethane; acetic acid; acetone;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) sodium amide / 1.) Et2O, liquid ammonia, -50 deg C - -40 deg C, 60 min, 2.) -50 deg C - -40 deg C, 100 min
2: toluene-p-sulphonic acid / methanol / 0.5 h / 70 °C
With
toluene-4-sulfonic acid; sodium amide;
In
methanol;