C₃₇H₄₅NO₆S

Base Information

• Chemical Name: C₃₇H₄₅NO₆S
• CAS No.: 196881-37-5
• Molecular Formula: C₃₇H₄₅NO₆S
• Molecular Weight: 631.833
• Mol file: 196881-37-5.mol

Synonyms:

Chemical Property of C₃₇H₄₅NO₆S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₇H₄₅NO₆S

There total 6 articles about C₃₇H₄₅NO₆S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,9-Androstadiene-3,17-dione (5173-46-6) → C37H45NO6S (196881-37-5)

Guidance literature:

Multi-step reaction with 6 steps

1: NaBH₄ / tetrahydrofuran; methanol / -10 °C

2: 1.) (EtO)3CH, pTsOH, 2.) pyridinium chlorochromate / 2.) CH₂Cl₂

3: KOtBu / tetrahydrofuran

4: H₂O₂, trifluoroacetophenone, Py / CH₂Cl₂

5: Mg, CuCl

6: CuI, Pd(OAc)2, PPh₃ / various solvent(s) / Heating

With pyridine; palladium diacetate; sodium tetrahydroborate; copper(l) iodide; 2,2,2-Trifluoroacetophenone; potassium tert-butylate; dihydrogen peroxide; toluene-4-sulfonic acid; magnesium; orthoformic acid triethyl ester; triphenylphosphine; pyridinium chlorochromate; copper(l) chloride; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1016/S0960-894X(97)00397-1

Reference yield:

ethylene deltenone (5571-36-8) → C37H45NO6S (196881-37-5)

Guidance literature:

Multi-step reaction with 4 steps

1: KOtBu / tetrahydrofuran

2: H₂O₂, trifluoroacetophenone, Py / CH₂Cl₂

3: Mg, CuCl

4: CuI, Pd(OAc)2, PPh₃ / various solvent(s) / Heating

With pyridine; palladium diacetate; copper(l) iodide; 2,2,2-Trifluoroacetophenone; potassium tert-butylate; dihydrogen peroxide; magnesium; triphenylphosphine; copper(l) chloride; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0960-894X(97)00397-1

Reference yield:

17-hydroxy-estra-4,9-dien-3-one → C37H45NO6S (196881-37-5)

Guidance literature:

Multi-step reaction with 5 steps

1: 1.) (EtO)3CH, pTsOH, 2.) pyridinium chlorochromate / 2.) CH₂Cl₂

2: KOtBu / tetrahydrofuran

3: H₂O₂, trifluoroacetophenone, Py / CH₂Cl₂

4: Mg, CuCl

5: CuI, Pd(OAc)2, PPh₃ / various solvent(s) / Heating

With pyridine; palladium diacetate; copper(l) iodide; 2,2,2-Trifluoroacetophenone; potassium tert-butylate; dihydrogen peroxide; toluene-4-sulfonic acid; magnesium; orthoformic acid triethyl ester; triphenylphosphine; pyridinium chlorochromate; copper(l) chloride; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0960-894X(97)00397-1

upstream raw materials:

4-bromoohenyl methyl sulfone

3,3-ethylenedioxy-5α,17β-dihydroxy-11β-[4-(N,N-dimethylamino)phenyl]-19-nor-17α-pregn-9-ene-21-ethyne

4,9-Androstadiene-3,17-dione

ethylene deltenone