Technology Process of C20H30N6O
There total 5 articles about C20H30N6O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: tetrabutyl ammonium fluoride / tetrahydrofuran / 15 h / 20 °C
2: tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate / toluene / 16 h / 110 °C
3: tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate / toluene / 16 h / 110 °C
4: hydrogenchloride; methanol / 1,4-dioxane / 0.03 h / Reflux
With
hydrogenchloride; methanol; tris-(dibenzylideneacetone)dipalladium(0); tetrabutyl ammonium fluoride; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate;
In
tetrahydrofuran; 1,4-dioxane; toluene;
2: Buchwald-Hartwig amination / 3: Buchwald-Hartwig amination;
DOI:10.1016/j.bmcl.2012.03.011
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate / toluene / 16 h / 110 °C
2: hydrogenchloride; methanol / 1,4-dioxane / 0.03 h / Reflux
With
hydrogenchloride; methanol; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate;
In
1,4-dioxane; toluene;
1: Buchwald-Hartwig amination;
DOI:10.1016/j.bmcl.2012.03.011