Technology Process of C16H18ClNO2
There total 9 articles about C16H18ClNO2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: titanium(IV) isopropylate; ammonia / methanol / 20 °C / Inert atmosphere
1.2: 3 h / 20 °C / Cooling with ice
2.1: pyridine; dmap / dichloromethane / 3 h / 20 °C
3.1: lipase B from Candida antarctica / water / 168 h / 45 °C / Enzymatic reaction
With
pyridine; titanium(IV) isopropylate; dmap; ammonia; lipase B from Candida antarctica;
In
methanol; dichloromethane; water;
DOI:10.1002/ejoc.201200330
- Guidance literature:
-
Multi-step reaction with 2 steps
1: pyridine; dmap / dichloromethane / 3 h / 20 °C
2: lipase B from Candida antarctica / water / 168 h / 45 °C / Enzymatic reaction
With
pyridine; dmap; lipase B from Candida antarctica;
In
dichloromethane; water;
DOI:10.1002/ejoc.201200330
- Guidance literature:
-
Multi-step reaction with 4 steps
1: diphenyl phosphoryl azide / toluene / Alkaline conditions
2: water; triphenylphosphine / tetrahydrofuran
3: pyridine; dmap / dichloromethane / 3 h / 20 °C
4: lipase B from Candida antarctica / water / 168 h / 45 °C / Enzymatic reaction
With
pyridine; dmap; diphenyl phosphoryl azide; water; triphenylphosphine; lipase B from Candida antarctica;
In
tetrahydrofuran; dichloromethane; water; toluene;
DOI:10.1002/ejoc.201200330
